Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.34 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.34 |
| ▸ | IGF1R | P08069 | 4/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
| ▸ | ATR | Q13535 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
| ▸ | DCPS | Q96C86 | 2/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | F9 | P00740 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18006417 | 0.85 | ALOX5 (0.34) | ALOX5CYSLTR2CYSLTR1EGFRSLC22A12 | |
| SCHEMBL26071012 | 0.80 | HSD17B10 (0.38) | CYSLTR2CYSLTR1IGF1REGFRPIK3CD | |
| SCHEMBL26070957 | 0.80 | MRGPRX4 (0.44) | ALOX5IGF1RPIK3CDPIK3CAPIK3CB | |
| SCHEMBL26071020 | 0.77 | NR1H2 (0.48) | IGF1REGFRSLC22A12 | |
| SCHEMBL26070959 | 0.77 | AKT1 (0.38) | CYSLTR2CYSLTR1IGF1REGFRPIK3CD | |
| SCHEMBL26070955 | 0.75 | AGXT (0.44) | CYSLTR2CYSLTR1IGF1RPIK3CDPIK3CA | |
| SCHEMBL26071043 | 0.75 | CHEK1 (0.43) | CYSLTR2CYSLTR1IGF1RSLC22A12NOTUM | |
| SCHEMBL26070963 | 0.74 | EGFR (0.43) | EGFRPIK3CA | |
| SCHEMBL26071083 | 0.74 | SLC22A12 (0.38) | IGF1RPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL26071075 | 0.73 | CYSLTR2 (0.36) | CYSLTR2CYSLTR1IGF1RPIK3CDPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219477-A1 | CYANOTRIAZOLE COMPOUNDS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2023-08-02 | — | — | EP | disclosed |