Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | INPPL1 | O15357 | 2/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | PRKDC | P78527 | 1/20 | 0.35 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | GRK2 | P25098 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18006430 | 0.85 | SLC22A12 (0.39) | SLC22A12NR1H2INPPL1KMT2AMEN1 | |
| SCHEMBL26071070 | 0.80 | SMN1; SMN2 (0.45) | DHFRKMT2AMEN1ROCK2GRK2 | |
| SCHEMBL26070911 | 0.79 | CYP2C9 (0.47) | KMT2AMEN1TSHR | |
| SCHEMBL26071067 | 0.77 | PTGER4 (0.40) | SLC22A12KMT2AMEN1TSHRPIK3CD | |
| SCHEMBL26071018 | 0.76 | NOTUM (0.38) | SLC22A12IGF1R | |
| SCHEMBL26071092 | 0.76 | IGF1R (0.39) | SLC22A12KMT2AMEN1PIK3CDPIK3CA | |
| SCHEMBL26070951 | 0.76 | SIRT2 (0.42) | BACE1DHFRHTR6IGF1R | |
| SCHEMBL26071083 | 0.75 | SLC22A12 (0.38) | SLC22A12KMT2AMEN1TSHRPIK3CD | |
| SCHEMBL26071016 | 0.75 | SLC22A12 (0.38) | SLC22A12TSHRROCK2ALOX5AP | |
| SCHEMBL26070898 | 0.74 | BTK (0.49) | SLC22A12TSHRPIK3CGFGFR2FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219477-A1 | CYANOTRIAZOLE COMPOUNDS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2023-08-02 | — | — | EP | disclosed |