Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | PRKDC | P78527 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CFD | P00746 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18006427 | 0.86 | TP53 (0.40) | PTGER4TP53POLBSLC22A12KDR | |
| SCHEMBL26071086 | 0.80 | SLC22A12 (0.40) | TP53POLBIGF1RSLC22A12SMN1; SMN2 | |
| SCHEMBL26071016 | 0.80 | SLC22A12 (0.38) | SLC22A12SMN1; SMN2JAK3MAPTALDH1A1 | |
| SCHEMBL26071072 | 0.77 | SLC22A12 (0.40) | IGF1RSLC22A12PIK3CDPIK3CAPIK3CB | |
| SCHEMBL26071092 | 0.74 | IGF1R (0.39) | IGF1RSLC22A12PIK3CDPIK3CAPIK3CB | |
| SCHEMBL26070959 | 0.74 | AKT1 (0.38) | IGF1RSLC22A12PIK3CDPIK3CAPIK3CB | |
| SCHEMBL26070963 | 0.74 | EGFR (0.43) | PTGER4PIK3CACFDMAPK1KDM4E | |
| SCHEMBL26071083 | 0.73 | SLC22A12 (0.38) | POLBIGF1RSLC22A12SMN1; SMN2PIK3CD | |
| SCHEMBL26071079 | 0.73 | IGF1R (0.35) | IGF1RSLC22A12SMN1; SMN2PIK3CDPIK3CA | |
| SCHEMBL26070898 | 0.73 | BTK (0.49) | TP53SLC22A12SMN1; SMN2PIK3CGMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219477-A1 | CYANOTRIAZOLE COMPOUNDS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2023-08-02 | — | — | EP | disclosed |