SCHEMBL26073636

SCHEMBL26073636

CCOC(=O)CC(C)OC(=O)C(O)CC(=O)O

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.38
MGAM O43451 1/20 0.38
GAA P10253 1/20 0.38
SI P14410 1/20 0.38
MGAM2 Q2M2H8 1/20 0.38
ALDH1A1 P00352 5/20 0.35
TRPA1 O75762 1/20 0.35
TSHR P16473 2/20 0.35
CYP3A4 P08684 2/20 0.34
ALOX15 P16050 2/20 0.34
TDP1 Q9NUW8 1/20 0.34
CHRM1 P11229 1/20 0.33
ADORA1 P30542 1/20 0.33
HSD17B10 Q99714 1/20 0.33
MEN1 O00255 1/20 0.33
NPC1 O15118 1/20 0.33
KMT2A Q03164 1/20 0.33
CYP1A2 P05177 1/20 0.32
SLC22A6 Q4U2R8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24205736 0.88 MGAM (0.39) MGAMGAASIMGAM2ALDH1A1
SCHEMBL2229574 0.82 SMN1; SMN2 (0.43) SMN1; SMN2ALDH1A1TSHRALOX15SLC22A6
SCHEMBL26073597 0.82 MGAM (0.43) MGAMGAASIMGAM2ALDH1A1
SCHEMBL24205730 0.82 MGAM (0.43) MGAMGAASIMGAM2ALDH1A1
SCHEMBL29124638 0.80 SMN1; SMN2 (0.37) SMN1; SMN2ALOX15SLC22A6
SCHEMBL29124707 0.80 MGAM (0.35) MGAMGAASIMGAM2ALDH1A1
SCHEMBL26073594 0.79 MGAM (0.38) MGAMGAASIMGAM2ALDH1A1
SCHEMBL26073653 0.79 SMN1; SMN2 (0.38) SMN1; SMN2MGAMGAASIMGAM2
Cadaverine Tartrate SCHEMBL30599689 0.79 MGAM (0.38) MGAMGAASIMGAM2ALDH1A1
SCHEMBL29249145 0.79 SMN1; SMN2 (0.40) SMN1; SMN2ALDH1A1TDP1CHRM1SLC22A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4146338-B1 PROCESS FOR PREPARING CARBOXYLIC ACID ESTERS OF HYDROXYBUTANOATES KETOLIPIX THERAPEUTICS GMBH (DE) 2024-07-24 EP disclosed
CN-116917264-A Process for preparing hydroxybutyric acid carboxylic ester 凯托利皮克斯治疗有限责任公司 2023-10-20 CN disclosed
US-20230303478-A1 PROCESS FOR PREPARING CARBOXYLIC ACID ESTERS OF HYDROXYBUTANOATES KETOLIPIX THERAPEUTICS GMBH (DE) 2023-09-28 US disclosed
EP-4146338-A1 PROCESS FOR PREPARING CARBOXYLIC ACID ESTERS OF HYDROXYBUTANOATES KetoLipix Therapeutics GmbH (DE) 2023-03-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230303478-A1 PROCESS FOR PREPARING CARBOXYLIC ACID ESTERS OF HYDROXYBUTANOATES HAO2, HSD17B12, HCAR3 SMN1; SMN2 3472/4885MGAM 651/4885GAA 1415/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.