Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 9/20 | 0.64 |
| ▸ | DHODH | Q02127 | 7/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23590255 | 0.91 | DHODH (0.69) | PLA2G2ADHODHKDM4EMEN1KMT2A | |
| SCHEMBL26074118 | 0.82 | PLA2G2A (0.64) | PLA2G2ADHODHKDM4EMEN1KMT2A | |
| SCHEMBL26075570 | 0.82 | DHODH (0.46) | PLA2G2ADHODHMEN1KMT2AALDH1A1 | |
| SCHEMBL23590121 | 0.82 | DHODH (0.55) | PLA2G2ADHODHKDM4EMEN1KMT2A | |
| SCHEMBL23590253 | 0.81 | DHODH (0.70) | PLA2G2ADHODHKDM4EMEN1KMT2A | |
| SCHEMBL26074099 | 0.81 | PLA2G2A (0.75) | PLA2G2ADHODHKDM4EMEN1KMT2A | |
| SCHEMBL23590336 | 0.81 | DHODH (0.57) | PLA2G2ADHODHKDM4EMEN1KMT2A | |
| SCHEMBL28475970 | 0.79 | PLA2G2A (0.78) | PLA2G2ADHODHKDM4EALDH1A1GAA | |
| SCHEMBL5792945 | 0.79 | PLA2G2A (0.78) | PLA2G2ADHODHMEN1KMT2AALDH1A1 | |
| SCHEMBL23590235 | 0.78 | DHODH (0.51) | DHODHKDM4EKMT2AALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230303710-A1 | METHODS AND COMPOSITIONS FOR INHIBITION OF DIHYDROOROTATE DEHYDROGENASE IN COMBINATION WITH AN ANTI-CD38 THERAPEUTIC AGENT | OHIO STATE INNOVATION FOUNDATION (US) | 2023-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230303710-A1 | METHODS AND COMPOSITIONS FOR INHIBITION OF DIHYDROOROTATE DEHYDROGENASE IN COMBINATION WITH AN ANTI-CD38 THERAPEUTIC AGENT | DHODH, CD38, DPYD | PLA2G2A 1679/4885DHODH 1/4885KDM4E 1396/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.