Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 14/20 | 0.42 |
| ▸ | ALOX5AP | P20292 | 13/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.38 |
| ▸ | ACP1 | P24666 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26075427 | 0.91 | LMNA (0.39) | FEN1ALOX5APMCHR1ACP1 | |
| SCHEMBL26075424 | 0.88 | KIF11 (0.43) | FEN1ALOX5APKIF11MCHR1ACP1 | |
| SCHEMBL26075138 | 0.88 | DHODH (0.41) | FEN1ALOX5AP | |
| SCHEMBL23590262 | 0.86 | ALOX5AP (0.48) | FEN1ALOX5APMCHR1APP | |
| SCHEMBL26075438 | 0.86 | ACP1 (0.39) | FEN1ALOX5APMCHR1ACP1 | |
| SCHEMBL26075292 | 0.84 | FEN1 (0.41) | FEN1ALOX5APMCHR1ACP1 | |
| SCHEMBL26075419 | 0.83 | KDM1A (0.46) | FEN1ALOX5APMCHR1APP | |
| SCHEMBL26075335 | 0.83 | ACP1 (0.50) | FEN1ALOX5APACP1APP | |
| SCHEMBL26075942 | 0.83 | DHFR (0.39) | FEN1ALOX5APMCHR1APP | |
| SCHEMBL26075367 | 0.82 | FEN1 (0.43) | FEN1ALOX5APACP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230303710-A1 | METHODS AND COMPOSITIONS FOR INHIBITION OF DIHYDROOROTATE DEHYDROGENASE IN COMBINATION WITH AN ANTI-CD38 THERAPEUTIC AGENT | OHIO STATE INNOVATION FOUNDATION (US) | 2023-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230303710-A1 | METHODS AND COMPOSITIONS FOR INHIBITION OF DIHYDROOROTATE DEHYDROGENASE IN COMBINATION WITH AN ANTI-CD38 THERAPEUTIC AGENT | DHODH, CD38, DPYD | FEN1 3899/4885ALOX5AP 821/4885KIF11 3743/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.