Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 6/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | RAD52 | P43351 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | NPY1R | P25929 | 1/20 | 0.51 |
| ▸ | NPY2R | P49146 | 1/20 | 0.51 |
| ▸ | TOP2A | P11388 | 1/20 | 0.48 |
| ▸ | HTR1B | P28222 | 3/20 | 0.47 |
| ▸ | HTR1A | P08908 | 3/20 | 0.46 |
| ▸ | HTR2A | P28223 | 3/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2607754 | 0.90 | HTR1B (0.51) | HTR7ALDH1A1LMNAMAPK1MAPT | |
| SCHEMBL2607777 | 0.79 | IFNAR1 (0.45) | ALDH1A1LMNAMAPK1MAPTRAD52 | |
| SCHEMBL1493101 | 0.79 | ALDH1A1 (0.44) | HTR7ALDH1A1LMNAMAPK1MAPT | |
| SCHEMBL6293960 | 0.79 | IFNAR1 (0.43) | ALDH1A1LMNAMAPK1MAPTRAD52 | |
| SCHEMBL2607673 | 0.76 | TLR8 (0.50) | ALDH1A1LMNAMAPK1MAPTSMN1; SMN2 | |
| SCHEMBL10682343 | 0.76 | RAD52 (0.41) | HTR7ALDH1A1LMNAMAPK1MAPT | |
| SCHEMBL1493098 | 0.76 | IFNAR1 (0.41) | ALDH1A1LMNAMAPK1MAPTRAD52 | |
| SCHEMBL29137793 | 0.76 | IFNAR1 (0.41) | ALDH1A1LMNAMAPK1MAPTRAD52 | |
| SCHEMBL8038665 | 0.76 | IFNAR1 (0.41) | ALDH1A1LMNAMAPK1MAPTRAD52 | |
| SCHEMBL2607764 | 0.76 | ALDH1A1 (0.44) | ALDH1A1LMNAMAPK1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130123326-A1 | ALLOSTERIC BINDING COMPOUNDS | REGION MIDTJYLLAND (DK) | 2013-05-16 | — | — | US | disclosed |
| US-20130123326-A1 | ALLOSTERIC BINDING COMPOUNDS | REGION MIDTJYLLAND (DK) | 2013-05-16 | — | — | US | disclosed |
| US-20120095048-A1 | ALLOSTERIC BINDING COMPOUNDS | REGION MIDT JYLLAND (DK) | 2012-04-19 | — | — | US | disclosed |
| US-20120095048-A1 | ALLOSTERIC BINDING COMPOUNDS | REGION MIDT JYLLAND (DK) | 2012-04-19 | — | — | US | disclosed |
| WO-2010094289-A1 | ALLOSTERIC BINDING COMPOUNDS | AARHUS UNIVERSITET (DK) | 2010-08-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120095048-A1 | ALLOSTERIC BINDING COMPOUNDS | GRIN2C, GRM2, GRIN2B | HTR7 228/4885ALDH1A1 3676/4885LMNA 4749/4885 |
| US-20130123326-A1 | ALLOSTERIC BINDING COMPOUNDS | GRIN2C, GRM2, GRIN2B | HTR7 228/4885ALDH1A1 3676/4885LMNA 4749/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.