SCHEMBL29137793

SCHEMBL29137793

ClCCSc1cccc2ccccc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IFNAR1 P17181 1/20 0.41
ALDH1A1 P00352 6/20 0.40
CYP1A2 P05177 3/20 0.40
CYP2A6 P11509 3/20 0.40
LMNA P02545 2/20 0.40
MAPK1 P28482 2/20 0.40
HDAC3 O15379 1/20 0.40
HDAC4 P56524 1/20 0.40
HDAC1 Q13547 1/20 0.40
HDAC7 Q8WUI4 1/20 0.40
HDAC2 Q92769 1/20 0.40
HDAC10 Q969S8 1/20 0.40
HDAC11 Q96DB2 1/20 0.40
HDAC8 Q9BY41 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40
HDAC9 Q9UKV0 1/20 0.40
HDAC5 Q9UQL6 1/20 0.40
NPY1R P25929 1/20 0.40
NPY2R P49146 1/20 0.40
CYP2C9 P11712 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25438709 0.87 HTR7 (0.31) CYP1A2CYP2A6
SCHEMBL6293960 0.83 IFNAR1 (0.43) IFNAR1ALDH1A1CYP1A2CYP2A6LMNA
SCHEMBL2607764 0.80 ALDH1A1 (0.44) IFNAR1ALDH1A1CYP1A2CYP2A6LMNA
SCHEMBL1493101 0.80 ALDH1A1 (0.44) IFNAR1ALDH1A1CYP1A2CYP2A6LMNA
SCHEMBL8038665 0.80 IFNAR1 (0.41) IFNAR1ALDH1A1CYP1A2CYP2A6LMNA
SCHEMBL1493098 0.80 IFNAR1 (0.41) IFNAR1ALDH1A1CYP1A2CYP2A6LMNA
SCHEMBL2607777 0.80 IFNAR1 (0.45) IFNAR1ALDH1A1CYP1A2CYP2A6LMNA
Hydrochloric Acid SCHEMBL11701871 0.78 ALDH1A1 (0.44) IFNAR1ALDH1A1CYP1A2LMNAMAPK1
SCHEMBL8044798 0.77 IFNAR1 (0.39) IFNAR1ALDH1A1CYP1A2CYP2A6LMNA
SCHEMBL11552030 0.77 HTR1B (0.47) IFNAR1ALDH1A1CYP1A2LMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118055922-A Naphthalene dithiol and its derivatives, and their preparation method and use 菅井化学工业株式会社 2024-05-17 CN disclosed
CN-117157277-A 1, 6-naphthalene dithiol and process for producing the same 菅井化学工业株式会社 2023-12-01 CN disclosed
WO-2023058449-A1 NAPHTHALENE DITHIOL AND DERIVATIVE THEREOF, AND PRODUCTION METHODS AND USES FOR SAME スガイ化学工業株式会社 2023-04-13 WO disclosed