Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26075291 | 0.90 | TDP1 (0.47) | ALDH1A1TDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL26390430 | 0.84 | TDP1 (0.53) | ALDH1A1TDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL6068448 | 0.80 | TDP1 (0.59) | ALDH1A1TDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL25633566 | 0.79 | RAB9A (0.52) | ALDH1A1TDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL21396290 | 0.79 | TDP1 (0.54) | ALDH1A1TDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL913073 | 0.79 | KMT2A (0.47) | ALDH1A1TDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL29562425 | 0.79 | KMT2A (0.47) | ALDH1A1TDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL4507007 | 0.78 | CA1 (0.62) | ALDH1A1TDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL25910700 | 0.78 | TDP1 (0.46) | ALDH1A1TDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL7323211 | 0.78 | TDP1 (0.53) | ALDH1A1TDP1KMT2ASLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230303538-A1 | GALECTIN-3 INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2023-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230303538-A1 | GALECTIN-3 INHIBITORS | LGALS3, LGALS1, LGALS3BP | ALDH1A1 2420/4885TDP1 1574/4885KMT2A 4621/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.