Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 17/20 | 0.43 |
| ▸ | IL1B | P01584 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL89465 | 0.82 | EPHX1 (0.44) | BRD4P2RX7 | |
| SCHEMBL9225021 | 0.82 | TSHR (0.39) | TSHR | |
| SCHEMBL13013428 | 0.79 | P2RX7 (0.41) | BRD4P2RX7TSHR | |
| SCHEMBL26077338 | 0.78 | TSHR (0.37) | TSHR | |
| SCHEMBL19127312 | 0.77 | BRD4 (0.41) | BRD4P2RX7TSHR | |
| SCHEMBL21551280 | 0.77 | SMYD3 (0.34) | BRD4TSHR | |
| SCHEMBL15869712 | 0.76 | LMNA (0.45) | BRD4P2RX7 | |
| SCHEMBL28519612 | 0.76 | HCRTR2 (0.43) | BRD4TSHR | |
| SCHEMBL7413884 | 0.76 | CYP3A4 (0.37) | TSHR | |
| SCHEMBL6368415 | 0.76 | CYP3A4 (0.37) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11773078-B2 | Furin inhibitors | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2023-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11773078-B2 | Furin inhibitors | FURIN, TGFB1, PCSK7 | BRD4 3263/4885P2RX7 4130/4885IL1B 279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.