Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 6/20 | 0.42 |
| ▸ | CNR2 | P34972 | 4/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21551173 | 0.88 | FURIN (0.44) | FURINPDE4BFFAR4SCN9A | |
| SCHEMBL26077353 | 0.84 | FURIN (0.41) | FURINCNR2PDE4BESR1MAPT | |
| SCHEMBL21551728 | 0.83 | GPR119 (0.47) | FURIN | |
| SCHEMBL30931840 | 0.83 | GPR119 (0.47) | FURIN | |
| SCHEMBL26077222 | 0.82 | FURIN (0.54) | FURINCNR2 | |
| SCHEMBL26077351 | 0.81 | FURIN (0.44) | FURINCNR2ESR1FFAR4 | |
| SCHEMBL26077354 | 0.79 | FURIN (0.65) | FURIN | |
| SCHEMBL26077249 | 0.78 | CNR2 (0.43) | FURINCNR2CNR1KDM4E | |
| SCHEMBL21551096 | 0.75 | FURIN (0.44) | FURINPDE4BTRPV1FFAR4SCN9A | |
| SCHEMBL26077221 | 0.75 | FURIN (0.51) | FURINCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11773078-B2 | Furin inhibitors | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2023-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11773078-B2 | Furin inhibitors | FURIN, TGFB1, PCSK7 | FURIN 1/4885CNR2 4165/4885PDE4B 1765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.