Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 7/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | FURIN | P09958 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.36 |
| ▸ | ADK | P55263 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26077224 | 0.86 | FURIN (0.40) | CNR2FURINNR1H2NR1H3AOC3 | |
| SCHEMBL26077222 | 0.84 | FURIN (0.54) | CNR2FURIN | |
| SCHEMBL26077247 | 0.83 | CNR2 (0.39) | CNR2CNR1FURINCACNA1H | |
| SCHEMBL21551124 | 0.82 | GPR119 (0.53) | ADK | |
| SCHEMBL30931826 | 0.82 | GPR119 (0.53) | ADK | |
| SCHEMBL29891789 | 0.82 | GPR119 (0.53) | ADK | |
| SCHEMBL26077248 | 0.81 | RAB9A (0.43) | CNR2FURINKDM4ECACNA1HNR1H2 | |
| SCHEMBL26077352 | 0.78 | FURIN (0.42) | CNR2CNR1FURINKDM4E | |
| SCHEMBL26077363 | 0.78 | FURIN (0.40) | FURIN | |
| SCHEMBL29927882 | 0.77 | ZAP70 (0.38) | FURIN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11773078-B2 | Furin inhibitors | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2023-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11773078-B2 | Furin inhibitors | FURIN, TGFB1, PCSK7 | CNR2 4165/4885CNR1 3600/4885FURIN 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.