Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | OGA | O60502 | 1/20 | 0.47 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.47 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.46 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.46 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26077251 | 0.86 | KIT (0.53) | ALDH1A1LMNAKDM4EHRH3P4HTM | |
| SCHEMBL25173787 | 0.86 | DGAT1 (0.50) | ALDH1A1LMNAMAPTNPC1RAB9A | |
| SCHEMBL30913560 | 0.86 | DGAT1 (0.50) | ALDH1A1LMNAMAPTNPC1RAB9A | |
| SCHEMBL20425289 | 0.85 | MCHR1 (0.45) | ALDH1A1LMNAMAPTNPC1RAB9A | |
| SCHEMBL25176689 | 0.85 | MCHR1 (0.48) | ALDH1A1LMNAMAPTNPC1RAB9A | |
| SCHEMBL30913568 | 0.85 | MCHR1 (0.48) | ALDH1A1LMNAMAPTNPC1RAB9A | |
| SCHEMBL11956908 | 0.85 | RAB9A (0.52) | ALDH1A1LMNAMAPTNPC1RAB9A | |
| SCHEMBL25170721 | 0.83 | MCHR1 (0.45) | ALDH1A1LMNAMAPTNPC1RAB9A | |
| SCHEMBL2309052 | 0.82 | NTRK1 (0.64) | MAPTNPC1RAB9AHTTPRMT5 | |
| SCHEMBL31104885 | 0.82 | PRMT5 (0.57) | ALDH1A1MAPTNPC1RAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11773078-B2 | Furin inhibitors | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2023-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11773078-B2 | Furin inhibitors | FURIN, TGFB1, PCSK7 | ALDH1A1 3733/4885LMNA 264/4885MAPT 3082/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.