Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 1/20 | 0.36 |
| ▸ | CTRC | Q99895 | 1/20 | 0.36 |
| ▸ | OGA | O60502 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | USP9X | Q93008 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16077532 | 0.93 | PTGS1 (0.37) | KLK7CTRCPTGS1PTGS2NTRK1 | |
| SCHEMBL16077536 | 0.82 | MPO (0.36) | OGA | |
| SCHEMBL14480216 | 0.79 | PTGS1 (0.35) | PTGS1PTGS2NTRK1USP9X | |
| SCHEMBL21603284 | 0.79 | PTGS1 (0.35) | PTGS1PTGS2NTRK1USP9X | |
| SCHEMBL21603239 | 0.79 | PTGS1 (0.38) | OGAPTGS1PTGS2NTRK1USP9X | |
| SCHEMBL16077528 | 0.78 | OGA (0.34) | KLK7CTRCOGAPTGS1PTGS2 | |
| SCHEMBL15070829 | 0.78 | SYK (0.36) | OGA | |
| SCHEMBL10175642 | 0.77 | NPC1 (0.33) | USP9X | |
| SCHEMBL20803906 | 0.74 | GRM5 (0.42) | — | |
| SCHEMBL23437847 | 0.74 | OGA (0.35) | OGAUSP9X |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8969342-B2 | Compounds and methods for treating mammalian gastrointestinal microbial infections | BRANDEIS UNIVERSITY (US) | 2015-03-03 | — | — | US | disclosed |
| US-20120101096-A1 | Compounds and Methods for Treating Mammalian Gastrointestinal Microbial Infections | University of Georgia Foundation, Inc. (US) | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101096-A1 | Compounds and Methods for Treating Mammalian Gastrointestinal Microbial Infections | IMPDH1, IMPDH2, IMPA1 | KLK7 3752/4885CTRC 3593/4885OGA 530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.