Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.42 |
| ▸ | FEN1 | P39748 | 15/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 15/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | MERTK | Q12866 | 1/20 | 0.34 |
| ▸ | NNMT | P40261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL84582 | 0.91 | GRM5 (0.50) | GRM5FEN1ALOX5AP | |
| SCHEMBL17427727 | 0.81 | GRM5 (0.33) | GRM5 | |
| SCHEMBL21201805 | 0.80 | GRM5 (0.44) | GRM5FEN1ALOX5APFLT3MERTK | |
| SCHEMBL2837929 | 0.76 | GRM5 (0.44) | GRM5FEN1ALOX5APNNMT | |
| SCHEMBL12600954 | 0.76 | NNMT (0.51) | GRM5FEN1ALOX5APNNMT | |
| SCHEMBL21603323 | 0.76 | GRM5 (0.43) | GRM5FEN1ALOX5AP | |
| SCHEMBL2607773 | 0.74 | KLK7 (0.36) | — | |
| SCHEMBL16077528 | 0.73 | OGA (0.34) | — | |
| SCHEMBL10224636 | 0.72 | NNMT (0.49) | GRM5FEN1ALOX5APNNMT | |
| SCHEMBL30172974 | 0.72 | GRM5 (0.40) | GRM5FEN1ALOX5APFLT3MERTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10633350-B2 | Diphenyl derivatives and uses thereof | NOVARTIS AG (CH) | 2020-04-28 | — | — | US | disclosed |
| US-20190077773-A1 | DIPHENYL DERIVATIVES AND USES THEREOF | NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH, INC. | 2019-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190077773-A1 | DIPHENYL DERIVATIVES AND USES THEREOF | MYOF, NGF, MUSK | GRM5 3136/4885FEN1 1892/4885ALOX5AP 3657/4885 |
| US-10633350-B2 | Diphenyl derivatives and uses thereof | MYOF, NGF, MUSK | GRM5 3136/4885FEN1 1892/4885ALOX5AP 3657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.