Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 2/20 | 0.53 |
| ▸ | MET | P08581 | 11/20 | 0.50 |
| ▸ | AXL | P30530 | 8/20 | 0.50 |
| ▸ | MERTK | Q12866 | 5/20 | 0.50 |
| ▸ | KDR | P35968 | 3/20 | 0.50 |
| ▸ | FLT3 | P36888 | 2/20 | 0.50 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.50 |
| ▸ | AURKA | O14965 | 1/20 | 0.50 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.50 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.50 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.50 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | LYN | P07948 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16136596 | 0.84 | EGFR (0.62) | SMN1; SMN2EGFRMETAXLMERTK | |
| SCHEMBL12468984 | 0.83 | ALDH1A1 (0.53) | ALDH1A1EGFRMETAXLMERTK | |
| SCHEMBL26075853 | 0.83 | MET (0.58) | METAXLMERTKKDRFLT3 | |
| SCHEMBL4112840 | 0.82 | GLA (0.63) | GLAALDH1A1SMN1; SMN2LMNATP53 | |
| SCHEMBL12561330 | 0.81 | PANK3 (0.53) | ALDH1A1SMN1; SMN2EGFRMETAXL | |
| SCHEMBL12285926 | 0.81 | MET (0.47) | ALDH1A1SMN1; SMN2EGFRMETAXL | |
| SCHEMBL26075729 | 0.81 | EGFR (0.53) | EGFRMETAXLMERTKKDR | |
| SCHEMBL10202155 | 0.79 | EGFR (0.50) | ALDH1A1EGFRMETAXLMERTK | |
| SCHEMBL13115623 | 0.79 | ALDH1A1 (0.63) | ALDH1A1SMN1; SMN2EGFRMETAXL | |
| SCHEMBL4405511 | 0.78 | FAAH (0.66) | EGFRMETAXLMERTKKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230303570-A1 | KINASE INHIBITORS AND USES THEREOF | ABM THERAPEUTICS CORP (US) | 2023-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230303570-A1 | KINASE INHIBITORS AND USES THEREOF | ERBB2, ERBB3, ERBB4 | GLA 4698/4885ALDH1A1 1859/4885SMN1; SMN2 2432/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.