Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 6/20 | 0.77 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.60 |
| ▸ | BRD2 | P25440 | 4/20 | 0.57 |
| ▸ | BRD3 | Q15059 | 4/20 | 0.57 |
| ▸ | BRDT | Q58F21 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.54 |
| ▸ | TERT | O14746 | 2/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20271941 | 0.87 | BRD4 (1.00) | BRD4ABCB1BRD2BRD3BRDT | |
| SCHEMBL30599697 | 0.87 | BRD4 (1.00) | BRD4ABCB1BRD2BRD3BRDT | |
| SCHEMBL26080234 | 0.85 | BRD4 (0.77) | BRD4ABCB1BRD2BRD3BRDT | |
| SCHEMBL17185537 | 0.85 | ABCB1 (0.70) | ABCB1KDM4EMEN1KMT2ANPC1 | |
| SCHEMBL26079993 | 0.83 | ABCB1 (0.80) | BRD4ABCB1BRD2BRD3BRDT | |
| SCHEMBL20291210 | 0.83 | BRD4 (0.67) | BRD4ABCB1BRD2BRD3BRDT | |
| SCHEMBL20291074 | 0.82 | BRD4 (0.71) | BRD4ABCB1BRD2BRD3BRDT | |
| SCHEMBL20291413 | 0.82 | BRD4 (0.71) | BRD4ABCB1BRD2BRD3BRDT | |
| SCHEMBL20291212 | 0.81 | BRD4 (0.72) | BRD4ABCB1BRD2BRD3BRDT | |
| SCHEMBL20291065 | 0.81 | BRD4 (0.73) | BRD4ABCB1BRD2BRD3BRDT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3554503-B1 | INHIBITORS OF BROMODOMAIN-CONTAINING PROTEIN 4 (BRD4) | UNIV TEXAS (US) | 2023-10-04 | — | — | EP | disclosed |