SCHEMBL260820

SCHEMBL260820

COS(=O)(=O)Cc1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.61
PRSS1 P07477 3/20 0.52
PRSS2 P07478 3/20 0.52
PRSS3 P35030 3/20 0.52
CA1 P00915 3/20 0.52
CA2 P00918 3/20 0.52
CA9 Q16790 2/20 0.52
FAAH O00519 1/20 0.52
ELANE P08246 1/20 0.52
PRTN3 P24158 1/20 0.52
CA5A P35218 1/20 0.52
F2 P00734 2/20 0.49
HTT P42858 2/20 0.47
MMP1 P03956 1/20 0.47
MMP2 P08253 1/20 0.47
MMP9 P14780 1/20 0.47
MMP8 P22894 1/20 0.47
MMP13 P45452 1/20 0.47
HSP90AA1 P07900 1/20 0.42
TXNRD1 Q16881 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28137631 0.98 KMT2A (0.59) KMT2APRSS1PRSS2PRSS3CA1
Nitrobenzene SCHEMBL27350133 0.86 HTT (0.65) KMT2AHTTMMP2TXNRD1ALDH1A1
SCHEMBL27977269 0.86 TXNRD1 (0.53) KMT2AHTTTXNRD1ALDH1A1MAPK1
SCHEMBL12474258 0.83 AGXT (0.47) KMT2ACA1CA2CA9
SCHEMBL29245395 0.83 KMT2A (0.57) KMT2APRSS1PRSS2PRSS3CA1
Dinitrophenylene SCHEMBL27894426 0.82 HTT (0.56) KMT2AHTTALDH1A1MAPK1TSHR
SCHEMBL1972890 0.81 KMT2A (0.65) KMT2APRSS1PRSS2PRSS3CA1
SCHEMBL28509967 0.80 CA2 (0.47) KMT2ACA2F2HTTALDH1A1
SCHEMBL14370973 0.80 CA1 (0.47) KMT2ACA1CA2CA9TXNRD1
SCHEMBL6916202 0.79 KMT2A (0.53) KMT2APRSS1PRSS2PRSS3CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4602358-A1 COMPOSITION AND METHOD FOR MEASURING CALCIUM HARDNESS IN PROCESS WATER Ecolab USA Inc. (US) 2025-08-20 EP claimed
WO-2024081636-A1 COMPOSITION AND METHOD FOR MEASURING CALCIUM HARDNESS IN PROCESS WATER ECOLAB USA INC. (US) 2024-04-18 WO claimed
US-20240125753-A1 COMPOSITION AND METHOD FOR MEASURING CALCIUM HARDNESS IN PROCESS WATER ECOLAB USA INC. 2024-04-18 US claimed
EP-4324928-A1 SYNTHETIC REAGENTS FOR ENZYME-CATALYSED ALKYLATION Universität Basel (CH) 2024-02-21 EP claimed
US-10351562-B2 Process for preparing methyl {4,6-diamino-2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-B]pyridin-3-yl]pyrimidin-5-yl}methylcarbamate and its purification for use as pharmaceutically active compound ADVERIO PHARMA GMBH (DE) 2019-07-16 US claimed
US-20180282329-A1 PROCESS FOR PREPARING METHYL {4,6-DIAMINO-2-[1-(2-FLUOROBENZYL)-1H-PYRAZOLO[3,4-B]PYRIDIN-3-YL]PYRIMIDIN-5-YL}METHYLCARBAMATE AND ITS PURIFICATION FOR USE AS PHARMACEUTICALLY ACTIVE COMPOUND ADVERIO PHARMA GMBH (DE) 2018-10-04 US claimed
EP-2444390-B1 Process for producing Lacosamide EUTICALS GMBH (DE) 2017-02-01 EP claimed
EP-2861643-A1 LATENT CATALYST FOR CURABLE COMPOSITIONS Dow Global Technologies LLC (US) 2015-04-22 EP claimed
US-20150087748-A1 LATENT CATALYST FOR CURABLE COMPOSITIONS BLUE CUBE IP LLC 2015-03-26 US claimed
US-8927634-B2 Phthalate-free isocyanurate formulations LANXESS DEUTSCHLAND GMBH (DE) 2015-01-06 US claimed
CN-1385919-A Electrolyte for lithium secondary battery and lithium secondary battery containing the same SAMSUNG SDI CO LTD (KR) 2002-12-18 CN claimed
US-20020107318-A1 Resin Composition NICHIAS CORPORATION (JP) 2002-08-08 US claimed
US-6291577-B1 ADMIXING WITH POLYISOCYANATE A MOISTURE SCAVENGING COMPOUND SUCH AS 2,6-DITERTIARYBUTYL HYDROXYTOLUENE AND 2-TERTIARYBUTYL HYDROXYTOLUENE AND ALKYL ESTER TOLUENESULFONIC ACID AND SOLVENT RHODIA INC. 2001-09-18 US claimed
EP-1029893-A2 Resin composition NICHIAS CORPORATION (JP) 2000-08-23 EP claimed
US-5286787-A Adding reactive polysiloxane, weatherproofing HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1994-02-15 US claimed
US-5225547-A Using an alkylation reagent and disubstituted formamide or acid amide as promoters SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1993-07-06 US claimed
EP-0216505-B1 POLYIMIDES, PREPARATION OF POLYIMIDES AND BLENDS OF POLYIMIDES ROHM AND HAAS COMPANY (US) 1993-02-24 EP claimed
US-4882095-A Preparation of alkoxy(iso)violanthrenediones BASF AKTIENGESELLSCHAFT (DE) 1989-11-21 US claimed
EP-0216505-A2 Polyimides, preparation of polyimides and blends of polyimides ROHM AND HAAS COMPANY (US) 1987-04-01 EP claimed
US-4051168-A TO FORM FLUOROALKYL AROMATIC COMPOUNDS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-09-27 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180282329-A1 PROCESS FOR PREPARING METHYL {4,6-DIAMINO-2-[1-(2-FLUOROBENZYL)-1H-PYRAZOLO[3,4-B]PYRIDIN-3-YL]PYRIMIDIN-5-YL}METHYLCARBAMATE AND ITS PURIFICATION FOR USE AS PHARMACEUTICALLY ACTIVE COMPOUND TPMT, AMD1, DPYD KMT2A 534/4885PRSS1 1054/4885PRSS2 1913/4885
US-10351562-B2 Process for preparing methyl {4,6-diamino-2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-B]pyridin-3-yl]pyrimidin-5-yl}methylcarbamate and its purification for use as pharmaceutically active compound TPMT, AMD1, DPYD KMT2A 603/4885PRSS1 1103/4885PRSS2 1972/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.