Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20298281 | 0.82 | TSHR (0.42) | TSHRLMNASMN1; SMN2MAPTCYP2D6 | |
| SCHEMBL229792 | 0.82 | TSHR (0.50) | TSHRLMNASMN1; SMN2MAPTCYP2D6 | |
| SCHEMBL182320 | 0.80 | MGAM (0.55) | TSHRLMNASMN1; SMN2MAPTCYP2D6 | |
| SCHEMBL29438274 | 0.80 | MGAM (0.55) | TSHRLMNASMN1; SMN2MAPTCYP2D6 | |
| SCHEMBL28875912 | 0.79 | LMNA (0.48) | TSHRLMNASMN1; SMN2MAPTCYP2D6 | |
| SCHEMBL28315849 | 0.79 | LMNA (0.48) | TSHRLMNASMN1; SMN2MAPTCYP2D6 | |
| SCHEMBL28727541 | 0.79 | LMNA (0.48) | TSHRLMNASMN1; SMN2MAPTCYP2D6 | |
| SCHEMBL18152012 | 0.79 | LMNA (0.48) | TSHRLMNASMN1; SMN2MAPTCYP2D6 | |
| SCHEMBL2608289 | 0.79 | LMNA (0.50) | TSHRLMNASMN1; SMN2MAPTCYP2D6 | |
| SCHEMBL20482195 | 0.78 | MGAM (0.52) | TSHRLMNASMN1; SMN2MAPTCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016156512-A1 | A PROCESS FOR PREPARING A CRYSTALLINE FORM OF SOFOSBUVIR | SANDOZ AG (CH) | 2016-10-06 | — | — | WO | disclosed |
| US-9012498-B2 | Biodegradable lipids for the delivery of active agents | ALNYLAM PHARMACEUTICALS, INC. (US) | 2015-04-21 | — | — | US | disclosed |
| US-20140308304-A1 | LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS | ALNYLAM PHARMACEUTICALS, INC. | 2014-10-16 | — | — | US | disclosed |
| US-8454857-B2 | Polymerizable liquid crystal compounds, polymerizable liquid crystal compositions, liquid crystalline polymers and optically anisotropic materials | ZEON CORPORATION (JP) | 2013-06-04 | — | — | US | disclosed |
| US-8262932-B2 | Polymerizable liquid crystal compound, polymerizable liquid crystal composition, polymer and film | FUJIFILM CORPORATION (JP) | 2012-09-11 | — | — | US | disclosed |
| US-8262932-B2 | Polymerizable liquid crystal compound, polymerizable liquid crystal composition, polymer and film | FUJIFILM CORPORATION (JP) | 2012-09-11 | — | — | US | disclosed |
| US-8262931-B2 | Polymerizable liquid crystal compound, polymerizable liquid crystal composition, polymer and film | FUJIFILM CORPORATION (JP) | 2012-09-11 | — | — | US | disclosed |
| US-8262931-B2 | Polymerizable liquid crystal compound, polymerizable liquid crystal composition, polymer and film | FUJIFILM CORPORATION (JP) | 2012-09-11 | — | — | US | disclosed |
| US-8158021-B2 | Polymerizable liquid crystal compound, polymerizable liquid crystal composition, liquid crystalline polymer, and optical anisotropic article | ZEON CORPORATION (JP) | 2012-04-17 | — | — | US | disclosed |
| US-20120027803-A1 | BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS | ALNYLAM PHARMACEUTICALS, INC. (US) | 2012-02-02 | — | — | US | disclosed |
| US-20110233464-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOUND, POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, POLYMER AND FILM | FUJIFILM CORPORATION (JP) | 2011-09-29 | — | — | US | disclosed |
| US-20110233464-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOUND, POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, POLYMER AND FILM | FUJIFILM CORPORATION (JP) | 2011-09-29 | — | — | US | disclosed |
| US-20110237768-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOUND, POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, POLYMER AND FILM | FUJIFILM CORPORATION (JP) | 2011-09-29 | — | — | US | disclosed |
| US-20110140041-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOUNDS, POLYMERIZABLE LIQUID CRYSTAL COMPOSITIONS, LIQUID CRYSTALLINE POLYMERS AND OPTICALLY ANISOTROPIC MATERIALS | ZEON CORPORATION (JP) | 2011-06-16 | — | — | US | disclosed |
| US-20100258764-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOUND, POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTALLINE POLYMER, AND OPTICAL ANISOTROPIC ARTICLE | ZEON CORPORATION (JP) | 2010-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120027803-A1 | BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS | LIPA, CETP, APOB | TSHR 2854/4885LMNA 165/4885SMN1; SMN2 2222/4885 |
| US-20110140041-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOUNDS, POLYMERIZABLE LIQUID CRYSTAL COMPOSITIONS, LIQUID CRYSTALLINE POLYMERS AND OPTICALLY ANISOTROPIC MATERIALS | CCNB1, CCNT1, CCNB2 | TSHR 4683/4885LMNA 58/4885SMN1; SMN2 3351/4885 |
| US-20100258764-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOUND, POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTALLINE POLYMER, AND OPTICAL ANISOTROPIC ARTICLE | LEO1, ZYX, CCNT1 | TSHR 4760/4885LMNA 316/4885SMN1; SMN2 4179/4885 |
| US-20140308304-A1 | LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS | NPC1L1, NPC1, CETP | TSHR 2889/4885LMNA 958/4885SMN1; SMN2 3213/4885 |
| US-20110237768-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOUND, POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, POLYMER AND FILM | SCO2, NR0B2, NR0B1 | TSHR 2025/4885LMNA 561/4885SMN1; SMN2 2702/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.