SCHEMBL2608301

SCHEMBL2608301

C=C(C)C(=O)NCCCCNC(=O)CCC(=O)OC(C)C

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 1/20 0.40
MAPT P10636 1/20 0.40
LMNA P02545 2/20 0.39
ALDH1A1 P00352 2/20 0.38
CASP2 P42575 1/20 0.37
TSHR P16473 2/20 0.36
NAAA Q02083 1/20 0.35
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
L3MBTL1 Q9Y468 2/20 0.33
HPGD P15428 1/20 0.33
POLB P06746 1/20 0.33
FAAH O00519 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2608292 0.94 MAPT (0.41) EPHX2MAPTLMNAALDH1A1TSHR
SCHEMBL12643038 0.87 EPHX2 (0.44) EPHX2ALDH1A1CASP2TSHRNAAA
SCHEMBL2608285 0.86 ALDH1A1 (0.39) EPHX2LMNAALDH1A1TSHR
SCHEMBL10081665 0.84 TSHR (0.43) EPHX2LMNACASP2TSHRNAAA
SCHEMBL2608288 0.83 TSHR (0.44) EPHX2MAPTLMNAALDH1A1CASP2
SCHEMBL12332603 0.83 EPHX2 (0.39) EPHX2MAPTLMNAALDH1A1CASP2
SCHEMBL21122975 0.81 GAA (0.45) EPHX2MAPTALDH1A1CASP2NAAA
SCHEMBL2608281 0.81 LMNA (0.37) EPHX2MAPTLMNAALDH1A1TSHR
SCHEMBL860819 0.80 EPHX2 (0.43) EPHX2MAPTLMNAALDH1A1CASP2
SCHEMBL2608277 0.79 ZDHHC20 (0.49) EPHX2MAPTLMNAALDH1A1CASP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11345180-B2 Display medium for assessment and method for manufacturing same ZEON CORPORATION (JP) 2022-05-31 US disclosed
US-20190184732-A1 DISPLAY MEDIUM FOR ASSESSMENT AND METHOD FOR MANUFACTURING SAME ZEON CORPORATION (JP) 2019-06-20 US disclosed
US-8262932-B2 Polymerizable liquid crystal compound, polymerizable liquid crystal composition, polymer and film FUJIFILM CORPORATION (JP) 2012-09-11 US disclosed
US-8262931-B2 Polymerizable liquid crystal compound, polymerizable liquid crystal composition, polymer and film FUJIFILM CORPORATION (JP) 2012-09-11 US disclosed
US-8158021-B2 Polymerizable liquid crystal compound, polymerizable liquid crystal composition, liquid crystalline polymer, and optical anisotropic article ZEON CORPORATION (JP) 2012-04-17 US disclosed
US-20110233464-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, POLYMER AND FILM FUJIFILM CORPORATION (JP) 2011-09-29 US disclosed
US-20100258764-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTALLINE POLYMER, AND OPTICAL ANISOTROPIC ARTICLE ZEON CORPORATION (JP) 2010-10-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100258764-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTALLINE POLYMER, AND OPTICAL ANISOTROPIC ARTICLE LEO1, ZYX, CCNT1 EPHX2 2270/4885MAPT 252/4885LMNA 316/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.