Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.70 |
| ▸ | GAA | P10253 | 1/20 | 0.70 |
| ▸ | RAB9A | P51151 | 1/20 | 0.70 |
| ▸ | CA1 | P00915 | 2/20 | 0.64 |
| ▸ | CA2 | P00918 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26111371 | 1.00 | NPC1 (0.70) | NPC1GAARAB9ACA1CA2 | |
| SCHEMBL26109411 | 0.93 | NPC1 (0.61) | NPC1GAARAB9ACA1CA2 | |
| SCHEMBL26083588 | 0.93 | NPC1 (0.61) | NPC1GAARAB9ACA1CA2 | |
| SCHEMBL31466742 | 0.87 | ALDH1A1 (0.64) | NPC1GAARAB9ACA1CA2 | |
| SCHEMBL26110309 | 0.87 | ALDH1A1 (0.64) | NPC1GAARAB9ACA1CA2 | |
| SCHEMBL26084136 | 0.87 | ALDH1A1 (0.64) | NPC1GAARAB9ACA1CA2 | |
| SCHEMBL10038052 | 0.84 | CA1 (0.67) | GAACA1CA2ALDH1A1SMN1; SMN2 | |
| SCHEMBL5512675 | 0.84 | CA1 (0.67) | GAACA1CA2ALDH1A1SMN1; SMN2 | |
| SCHEMBL26084139 | 0.84 | NPC1 (0.51) | NPC1GAARAB9ACA1CA2 | |
| SCHEMBL741706 | 0.83 | NPC1 (1.00) | NPC1GAARAB9ACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192782-A2 | SMALL MOLECULE INHIBITORS OF LANOSTEROL SYNTHASE | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-10-05 | — | — | WO | disclosed |