Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31466742 | 0.86 | ALDH1A1 (0.64) | NPC1GAARAB9AALDH1A1KMT2A | |
| SCHEMBL26084136 | 0.86 | ALDH1A1 (0.64) | NPC1GAARAB9AALDH1A1KMT2A | |
| SCHEMBL26110309 | 0.86 | ALDH1A1 (0.64) | NPC1GAARAB9AALDH1A1KMT2A | |
| SCHEMBL26083593 | 0.84 | NPC1 (0.70) | NPC1GAARAB9AALDH1A1KMT2A | |
| SCHEMBL26111371 | 0.84 | NPC1 (0.70) | NPC1GAARAB9AALDH1A1KMT2A | |
| SCHEMBL26109411 | 0.81 | NPC1 (0.61) | NPC1GAARAB9AALDH1A1KMT2A | |
| SCHEMBL26083588 | 0.81 | NPC1 (0.61) | NPC1GAARAB9AALDH1A1KMT2A | |
| SCHEMBL26083644 | 0.77 | ALDH1A1 (0.53) | NPC1GAARAB9AALDH1A1KMT2A | |
| SCHEMBL26108825 | 0.77 | ALDH1A1 (0.53) | NPC1GAARAB9AALDH1A1KMT2A | |
| SCHEMBL26109436 | 0.77 | ALDH1A1 (0.51) | NPC1GAARAB9AALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192782-A2 | SMALL MOLECULE INHIBITORS OF LANOSTEROL SYNTHASE | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-10-05 | — | — | WO | disclosed |