Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.43 |
| ▸ | PTPRC | P08575 | 1/20 | 0.43 |
| ▸ | FABP7 | O15540 | 1/20 | 0.42 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10554690 | 0.90 | ALDH1A1 (0.53) | ALDH1A1KMT2ASMN1; SMN2MEN1PTPN1 | |
| SCHEMBL27582847 | 0.86 | RXRA (0.49) | ALDH1A1KMT2AMEN1HPGDSLC6A2 | |
| SCHEMBL3045824 | 0.85 | ALDH1A1 (0.49) | ALDH1A1KMT2ASMN1; SMN2MEN1TP53 | |
| SCHEMBL27600184 | 0.84 | PARP10 (0.52) | ALDH1A1KMT2ASMN1; SMN2HPGDPTPN1 | |
| SCHEMBL3379309 | 0.83 | SMN1; SMN2 (0.41) | ALDH1A1KMT2ASMN1; SMN2MEN1TP53 | |
| SCHEMBL6135476 | 0.80 | NPSR1 (0.50) | ALDH1A1KMT2ASMN1; SMN2MEN1HPGD | |
| SCHEMBL6135621 | 0.80 | NPSR1 (0.50) | ALDH1A1KMT2ASMN1; SMN2MEN1HPGD | |
| SCHEMBL204187 | 0.80 | NPSR1 (0.50) | ALDH1A1KMT2ASMN1; SMN2MEN1HPGD | |
| SCHEMBL7483779 | 0.80 | ALDH1A1 (0.56) | ALDH1A1KMT2ASMN1; SMN2MEN1HPGD | |
| SCHEMBL1809268 | 0.78 | ALDH1A1 (0.58) | ALDH1A1KMT2ASMN1; SMN2MEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11780845-B2 | FGFR inhibitors and methods of use thereof | RELAY THERAPEUTICS, INC. (US) | 2023-10-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11780845-B2 | FGFR inhibitors and methods of use thereof | FGFR3, FGFR2, FGFR1 | ALDH1A1 1774/4885KMT2A 1423/4885SMN1; SMN2 3600/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.