Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL204187 | 1.00 | NPSR1 (0.50) | NPSR1LMNACYP1A2SMN1; SMN2ALDH1A1 | |
| SCHEMBL6135476 | 1.00 | NPSR1 (0.50) | NPSR1LMNACYP1A2SMN1; SMN2ALDH1A1 | |
| SCHEMBL8907388 | 0.86 | CNR2 (0.44) | NPSR1LMNACYP1A2SMN1; SMN2CYP2C9 | |
| SCHEMBL13070710 | 0.83 | TSHR (0.40) | NPSR1LMNACYP1A2SMN1; SMN2ALDH1A1 | |
| SCHEMBL2490473 | 0.83 | CYP3A4 (0.58) | NPSR1CYP1A2SMN1; SMN2ALDH1A1CYP2C9 | |
| SCHEMBL18982867 | 0.83 | ALDH1A1 (0.49) | NPSR1LMNACYP1A2SMN1; SMN2ALDH1A1 | |
| SCHEMBL9211 | 0.83 | ALDH1A1 (0.49) | NPSR1LMNACYP1A2SMN1; SMN2ALDH1A1 | |
| SCHEMBL1455978 | 0.83 | PIN1 (0.51) | NPSR1SMN1; SMN2ALDH1A1CYP2C19KMT2A | |
| SCHEMBL27731921 | 0.83 | PIN1 (0.51) | NPSR1SMN1; SMN2ALDH1A1CYP2C19KMT2A | |
| SCHEMBL27752471 | 0.83 | PIN1 (0.51) | NPSR1SMN1; SMN2ALDH1A1CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811616-B1 | Salts of 3-(2-(4-(4-(Amino-imino-methyl)-phenyl)-4-methyl-2,5-dioxo-imidazolidin-1-yl)-acetylamino)-3-phenyl-propionic acid ethylester | AVENTIS PHARMA GMBH (DE) | 2005-05-04 | — | — | EP | disclosed |
| EP-0823898-B1 | HYDANTOINE DERIVATIVES AS INTERMEDIATE PRODUCTS FOR ACTIVE PHARMACEUTICAL AGENTS | HOECHST AG (DE) | 2003-02-26 | — | — | EP | disclosed |
| EP-0823898-A1 | HYDANTOINE DERIVATIVES AS INTERMEDIATE PRODUCTS FOR ACTIVE PHARMACEUTICAL AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-02-18 | — | — | EP | disclosed |
| EP-0811616-A1 | Salts of 3-(2-(4-(4-(Amino-imino-methyl)-phenyl)-4-methyl-2,5-dioxo-imidazolidin-1-yl)-acetylamino)-3-phenyl-propionic acid ethylester | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-12-10 | — | — | EP | disclosed |
| WO-1996033976-A1 | HYDANTOINE DERIVATIVES AS INTERMEDIATE PRODUCTS FOR ACTIVE PHARMACEUTICAL AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-10-31 | — | — | WO | disclosed |