Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26089410 | 0.94 | RAB9A (0.52) | GAAMAPTCYP1A2CYP2C19MAPK8 | |
| SCHEMBL30346013 | 0.89 | MAPT (0.52) | GAAMAPTPOLBCYP1A2CYP2D6 | |
| SCHEMBL26087395 | 0.89 | MAPT (0.52) | GAAMAPTPOLBCYP1A2CYP2D6 | |
| SCHEMBL26090725 | 0.89 | POLB (0.43) | GAAMAPTPOLBCYP1A2CYP2D6 | |
| SCHEMBL26089403 | 0.83 | RAB9A (0.52) | GAAMAPTCYP1A2CYP2C19MAPK8 | |
| SCHEMBL26091326 | 0.82 | MEN1 (0.53) | MAPTPOLBSMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL26090807 | 0.80 | ALDH1A1 (0.52) | GAAMAPTPOLBRAB9ANPC1 | |
| SCHEMBL26087980 | 0.80 | KCNQ2 (0.43) | GAAMAPTPOLBMAPK8RAB9A | |
| SCHEMBL26087452 | 0.79 | SMN1; SMN2 (0.52) | GAAMAPTRAB9ASMN1; SMN2TP53 | |
| SCHEMBL26088016 | 0.79 | GAA (0.58) | GAAMAPTSMN1; SMN2KMT2ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023068852-A1 | BENZOTHIOPHENE-1,1-DIOXIDE DERIVATIVE COMPOUND AS STAT3 INHIBITOR, AND USE THEREOF | 주식회사 프롬바이오 | 2023-04-27 | — | — | WO | claimed |
| WO-2023068852-A1 | BENZOTHIOPHENE-1,1-DIOXIDE DERIVATIVE COMPOUND AS STAT3 INHIBITOR, AND USE THEREOF | 주식회사 프롬바이오 | 2023-04-27 | — | — | WO | disclosed |