Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30346013 | 0.94 | MAPT (0.52) | RAB9ACA12CA9ALDH1A1SMN1; SMN2 | |
| SCHEMBL26087395 | 0.94 | MAPT (0.52) | RAB9ACA12CA9ALDH1A1SMN1; SMN2 | |
| SCHEMBL26089410 | 0.89 | RAB9A (0.52) | RAB9ACA12CA9ALDH1A1SMN1; SMN2 | |
| SCHEMBL26090717 | 0.84 | CA12 (0.45) | RAB9ACA12CA9ALDH1A1SMN1; SMN2 | |
| SCHEMBL26087397 | 0.83 | GAA (0.52) | RAB9ACA12CA9ALDH1A1SMN1; SMN2 | |
| SCHEMBL179015 | 0.82 | RAB9A (0.71) | RAB9AALDH1A1SMN1; SMN2HTTMAPT | |
| SCHEMBL30346080 | 0.80 | MEN1 (0.53) | ALDH1A1SMN1; SMN2HTTMAPTSTAT3 | |
| SCHEMBL30346152 | 0.80 | STAT3 (0.48) | RAB9ACA12CA9ALDH1A1SMN1; SMN2 | |
| SCHEMBL30345669 | 0.80 | ALDH1A1 (0.52) | CA12CA9ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL26087977 | 0.80 | STAT3 (0.48) | RAB9ACA12CA9ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023068852-A1 | BENZOTHIOPHENE-1,1-DIOXIDE DERIVATIVE COMPOUND AS STAT3 INHIBITOR, AND USE THEREOF | 주식회사 프롬바이오 | 2023-04-27 | — | — | WO | claimed |
| WO-2023068852-A1 | BENZOTHIOPHENE-1,1-DIOXIDE DERIVATIVE COMPOUND AS STAT3 INHIBITOR, AND USE THEREOF | 주식회사 프롬바이오 | 2023-04-27 | — | — | WO | disclosed |