Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | FPR1 | P21462 | 2/20 | 0.39 |
| ▸ | FPR2 | P25090 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | CCNC | P24863 | 2/20 | 0.38 |
| ▸ | CDK8 | P49336 | 2/20 | 0.38 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.37 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | CCR3 | P51677 | 2/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26435433 | 1.00 | EPHX2 (0.42) | EPHX2FPR1FPR2NPC1RAB9A | |
| SCHEMBL30408943 | 1.00 | EPHX2 (0.42) | EPHX2FPR1FPR2NPC1RAB9A | |
| SCHEMBL26435443 | 0.91 | CXCR3 (0.47) | EPHX2CXCR3 | |
| SCHEMBL26090150 | 0.90 | EPHX2 (0.45) | EPHX2NPC1RAB9ACCNCCDK8 | |
| SCHEMBL26090446 | 0.90 | FPR2 (0.39) | EPHX2FPR1FPR2CCNCCDK8 | |
| SCHEMBL30407826 | 0.90 | EPHX2 (0.45) | EPHX2NPC1RAB9ACCNCCDK8 | |
| SCHEMBL26435659 | 0.90 | FPR2 (0.39) | EPHX2FPR1FPR2CCNCCDK8 | |
| SCHEMBL26435439 | 0.90 | EPHX2 (0.45) | EPHX2NPC1RAB9ACCNCCDK8 | |
| SCHEMBL30407271 | 0.89 | FPR1 (0.43) | EPHX2FPR1FPR2RAB9ACCNC | |
| SCHEMBL26087705 | 0.89 | FPR1 (0.43) | EPHX2FPR1FPR2RAB9ACCNC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023069708-A1 | COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND USES THEREOF | MONTE ROSA THERAPEUTICS, INC. (US) | 2023-04-27 | — | — | WO | disclosed |