Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30378636 | 1.00 | DRD2 (0.44) | DRD2DRD4OPRL1LMNAALDH1A1 | |
| SCHEMBL30379061 | 0.92 | LMNA (0.46) | DRD2DRD4OPRL1LMNAALDH1A1 | |
| SCHEMBL30910065 | 0.92 | LMNA (0.46) | DRD2DRD4OPRL1LMNAALDH1A1 | |
| SCHEMBL26092275 | 0.92 | LMNA (0.46) | DRD2DRD4OPRL1LMNAALDH1A1 | |
| SCHEMBL26091739 | 0.92 | LMNA (0.46) | DRD2DRD4OPRL1LMNAALDH1A1 | |
| SCHEMBL26091848 | 0.89 | KDM4E (0.47) | DRD2DRD4LMNAALDH1A1MEN1 | |
| SCHEMBL30379525 | 0.89 | KDM4E (0.47) | DRD2DRD4LMNAALDH1A1MEN1 | |
| SCHEMBL26090735 | 0.87 | LMNA (0.43) | DRD2DRD4OPRL1LMNAMAPT | |
| SCHEMBL30379486 | 0.87 | LMNA (0.43) | DRD2DRD4OPRL1LMNAMAPT | |
| SCHEMBL30379057 | 0.85 | CHRM2 (0.44) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118119612-A | Novel compounds and pharmaceutical compositions comprising the same | 萨皮恩斯生物有限公司 | 2024-05-31 | — | — | CN | claimed |
| WO-2023068755-A1 | NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 사피엔스바이오 | 2023-04-27 | — | — | WO | claimed |
| CN-118119612-A | Novel compounds and pharmaceutical compositions comprising the same | 萨皮恩斯生物有限公司 | 2024-05-31 | — | — | CN | disclosed |
| WO-2023068755-A1 | NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 사피엔스바이오 | 2023-04-27 | — | — | WO | disclosed |
| WO-2023068755-A1 | NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 사피엔스바이오 | 2023-04-27 | — | — | WO | disclosed |