SCHEMBL30379486

SCHEMBL30379486

O=C(CCN1CCNCC1)N1CCN(C2CCCCC2)c2ccccc21

nearest known ligand 0.43

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 2/20 0.43
▸ KDM1A O60341 1/20 0.40
▸ GPBAR1 Q8TDU6 6/20 0.39
▸ OPRL1 P41146 1/20 0.39
▸ DRD2 P14416 1/20 0.39
▸ DRD4 P21917 1/20 0.39
▸ TP53 P04637 1/20 0.39
▸ MAPT P10636 1/20 0.39
▸ HTR2C P28335 1/20 0.38
▸ HTR2B P41595 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26090735 1.00 LMNA (0.43) LMNAKDM1AGPBAR1OPRL1DRD2
SCHEMBL26092275 0.91 LMNA (0.46) LMNAGPBAR1OPRL1DRD2DRD4
SCHEMBL30379061 0.91 LMNA (0.46) LMNAGPBAR1OPRL1DRD2DRD4
SCHEMBL30910065 0.91 LMNA (0.46) LMNAGPBAR1OPRL1DRD2DRD4
SCHEMBL26091739 0.91 LMNA (0.46) LMNAGPBAR1OPRL1DRD2DRD4
SCHEMBL26087873 0.87 DRD2 (0.44) LMNAGPBAR1OPRL1DRD2DRD4
SCHEMBL30378636 0.87 DRD2 (0.44) LMNAGPBAR1OPRL1DRD2DRD4
SCHEMBL26089828 0.81 LMNA (0.47) LMNAGPBAR1TP53MAPT
SCHEMBL30378966 0.81 LMNA (0.47) LMNAGPBAR1TP53MAPT
SCHEMBL30379057 0.79 CHRM2 (0.44) LMNATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250002464-A1 NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME SAPIENSBIO INC. (KR) 2025-01-02 — — US claimed
EP-4421070-A1 NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME Sapiensbio Inc. (KR) 2024-08-28 — — EP claimed
CN-118119612-A Novel compounds and pharmaceutical compositions comprising the same 萨皮恩斯生物有限公司 2024-05-31 — — CN claimed
US-20250002464-A1 NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME SAPIENSBIO INC. (KR) 2025-01-02 — — US disclosed
EP-4421070-A1 NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME Sapiensbio Inc. (KR) 2024-08-28 — — EP disclosed
CN-118119612-A Novel compounds and pharmaceutical compositions comprising the same 萨皮恩斯生物有限公司 2024-05-31 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250002464-A1 NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME RHOA, ACTR2, MFAP1 LMNA 1071/4885KDM1A 1774/4885GPBAR1 1046/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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