SCHEMBL26089261

SCHEMBL26089261

CC(C)(C)C1CNc2ccccc2N1C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 1/20 0.39
HSD17B3 P37058 1/20 0.38
MEN1 O00255 5/20 0.37
KMT2A Q03164 5/20 0.37
GAA P10253 2/20 0.37
BRPF1 P55201 1/20 0.36
CRHBP P24387 1/20 0.36
CRHR2 Q13324 1/20 0.36
MTNR1A P48039 1/20 0.35
MTNR1B P49286 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
BRD4 O60885 2/20 0.35
IDH1 O75874 2/20 0.34
RIPK1 Q13546 2/20 0.34
SCN9A Q15858 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28582091 0.81 RBP4 (0.34) MEN1KMT2ACRHBPCRHR2BRD4
SCHEMBL28092792 0.77 HSD17B3 (0.38) EPHX2HSD17B3MEN1KMT2AGAA
SCHEMBL10226402 0.75 GAA (0.41) EPHX2HSD17B3MEN1KMT2AGAA
SCHEMBL3796963 0.74 NOTUM (0.51)
SCHEMBL29220851 0.73 HTT (0.38) HSD17B3MEN1KMT2AGAABRPF1
SCHEMBL29220793 0.73 XIAP (0.37) HSD17B3MEN1KMT2AGAABRPF1
SCHEMBL28092690 0.72 GAA (0.36) HSD17B3MEN1KMT2AGAABRPF1
SCHEMBL29220790 0.72 MEN1 (0.40) MEN1KMT2AGAASMN1; SMN2BRD4
SCHEMBL16722422 0.71 NOTUM (0.55) HSD17B3MEN1KMT2AGAABRPF1
SCHEMBL16722424 0.71 NOTUM (0.55) HSD17B3MEN1KMT2AGAABRPF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250002464-A1 NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME SAPIENSBIO INC. (KR) 2025-01-02 US disclosed
EP-4421070-A1 NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME Sapiensbio Inc. (KR) 2024-08-28 EP disclosed
WO-2023068755-A1 NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME 주식회사 사피엔스바이오 2023-04-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250002464-A1 NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME RHOA, ACTR2, MFAP1 EPHX2 2233/4885HSD17B3 4030/4885MEN1 4510/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.