Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 1/20 | 0.34 |
| ▸ | MYC | P01106 | 1/20 | 0.34 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.31 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16721417 | 0.82 | PDK1 (0.37) | RBP4MYCNR4A1ARBRD4 | |
| SCHEMBL26089261 | 0.81 | EPHX2 (0.39) | BRD4MEN1KMT2ACRHBPCRHR2 | |
| SCHEMBL14321151 | 0.77 | PDK1 (0.39) | RBP4MYCNR4A1BRD4MEN1 | |
| SCHEMBL16721158 | 0.74 | NOTUM (0.40) | BRD4MEN1KMT2APDK1PDK2 | |
| SCHEMBL16721159 | 0.74 | NOTUM (0.40) | BRD4MEN1KMT2APDK1PDK2 | |
| SCHEMBL29014075 | 0.74 | LMNA (0.38) | RBP4MYCNR4A1BRD4MEN1 | |
| SCHEMBL16722313 | 0.73 | AR (0.36) | RBP4MYCNR4A1ARMEN1 | |
| SCHEMBL16722311 | 0.73 | AR (0.36) | RBP4MYCNR4A1ARMEN1 | |
| SCHEMBL16722722 | 0.71 | HTT (0.35) | RBP4BRD4MEN1KMT2APDK1 | |
| SCHEMBL16721384 | 0.71 | HSD17B3 (0.38) | BRD4MEN1KMT2APDK1PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112839931-A | 1,2,3, 4-tetrahydroquinoxaline derivative and preparation method and application thereof | 上海和誉生物医药科技有限公司 | 2021-05-25 | — | — | CN | disclosed |