Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.46 |
| ▸ | MEN1 | O00255 | 8/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | HTT | P42858 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.39 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20560639 | 0.85 | KMT2A (0.44) | KMT2AMEN1MAPTLMNAHTT | |
| SCHEMBL30739739 | 0.84 | MEN1 (0.58) | KMT2AMEN1MAPTHTTSMN1; SMN2 | |
| SCHEMBL18764592 | 0.81 | TGM2 (0.48) | KMT2AMEN1MAPTLMNAHTT | |
| SCHEMBL169338 | 0.81 | POLB (0.54) | KMT2AMEN1MAPTLMNASMN1; SMN2 | |
| SCHEMBL169339 | 0.81 | POLB (0.54) | KMT2AMEN1MAPTLMNASMN1; SMN2 | |
| SCHEMBL16831668 | 0.81 | ALDH1A1 (0.60) | KMT2AMEN1MAPTLMNASMN1; SMN2 | |
| SCHEMBL16831666 | 0.81 | ALDH1A1 (0.60) | KMT2AMEN1MAPTLMNASMN1; SMN2 | |
| SCHEMBL29132780 | 0.81 | KMT2A (0.42) | KMT2AMEN1MAPTLMNAHTT | |
| SCHEMBL20560220 | 0.81 | KMT2A (0.40) | KMT2AMEN1MAPTLMNAHTT | |
| SCHEMBL31067320 | 0.79 | HPGD (0.45) | KMT2AMEN1MAPTLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023067354-A1 | HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF CANCER | ARTIOS PHARMA LIMITED (GB) | 2023-04-27 | — | — | WO | disclosed |