Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 8/20 | 0.38 |
| ▸ | NPC1 | O15118 | 6/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4090578 | 0.83 | ALDH1A1 (0.41) | KMT2AMEN1MAPTSMN1; SMN2HTT | |
| SCHEMBL1855978 | 0.83 | ALDH1A1 (0.45) | KMT2AMEN1MAPTSMN1; SMN2HTT | |
| SCHEMBL22325730 | 0.81 | ALDH1A1 (0.44) | KMT2AMEN1MAPTSMN1; SMN2HTT | |
| SCHEMBL2958662 | 0.81 | KAT2B (0.41) | KMT2AMEN1MAPTSMN1; SMN2HTT | |
| SCHEMBL26089934 | 0.81 | KMT2A (0.46) | KMT2AMEN1MAPTSMN1; SMN2HTT | |
| SCHEMBL3141471 | 0.80 | MAPT (0.51) | KMT2AMEN1MAPTSMN1; SMN2HTT | |
| SCHEMBL20560639 | 0.80 | KMT2A (0.44) | KMT2AMEN1MAPTSMN1; SMN2HTT | |
| SCHEMBL240574 | 0.80 | TDP1 (0.52) | MAPTSMN1; SMN2ALDH1A1TDP1GPR35 | |
| SCHEMBL1396225 | 0.79 | GPR35 (0.58) | KMT2AMEN1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL20560220 | 0.78 | KMT2A (0.40) | KMT2AMEN1MAPTSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117203202-A | Quinoxaline derivative and use thereof | 黑钻治疗公司 | 2023-12-08 | — | — | CN | disclosed |