SCHEMBL26090474 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	IL1B	P01584	14/20	0.45

▸	NLRP3	Q96P20	9/20	0.45

▸	TNF	P01375	2/20	0.42

▸	KCNH2	Q12809	1/20	0.41

▸	JUN	P05412	2/20	0.35

▸	MAPK8	P45983	2/20	0.35

▸	MAPK9	P45984	2/20	0.35

▸	CDK2	P24941	1/20	0.35

▸	MAPK10	P53779	1/20	0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL26090487	1.00	IL1B (0.45)	IL1BNLRP3TNFKCNH2JUN
SCHEMBL26090457	1.00	IL1B (0.45)	IL1BNLRP3TNFKCNH2JUN
SCHEMBL26440693	0.87	NLRP3 (0.34)	IL1BNLRP3TNFKCNH2JUN
SCHEMBL30375248	0.87	NLRP3 (0.34)	IL1BNLRP3TNFKCNH2JUN
SCHEMBL26090434	0.87	IL1B (0.50)	IL1BNLRP3TNFKCNH2
SCHEMBL26090420	0.87	IL1B (0.50)	IL1BNLRP3TNFKCNH2
SCHEMBL26090664	0.86	IL1B (0.49)	IL1BNLRP3TNFKCNH2
SCHEMBL26090675	0.86	IL1B (0.49)	IL1BNLRP3TNFKCNH2
SCHEMBL31072365	0.84	IL1B (0.47)	IL1BNLRP3TNFKCNH2
SCHEMBL26439655	0.84	IL1B (0.47)	IL1BNLRP3TNFKCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2023066377-A1	NITROGEN-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF	索智生物科技（浙江）有限公司	2023-04-27	—	—	WO	disclosed