Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1B | P01584 | 14/20 | 0.45 |
| ▸ | NLRP3 | Q96P20 | 9/20 | 0.45 |
| ▸ | TNF | P01375 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | JUN | P05412 | 2/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26090474 | 1.00 | IL1B (0.45) | IL1BNLRP3TNFKCNH2JUN | |
| SCHEMBL26090457 | 1.00 | IL1B (0.45) | IL1BNLRP3TNFKCNH2JUN | |
| SCHEMBL26440693 | 0.87 | NLRP3 (0.34) | IL1BNLRP3TNFKCNH2JUN | |
| SCHEMBL30375248 | 0.87 | NLRP3 (0.34) | IL1BNLRP3TNFKCNH2JUN | |
| SCHEMBL26090434 | 0.87 | IL1B (0.50) | IL1BNLRP3TNFKCNH2 | |
| SCHEMBL26090420 | 0.87 | IL1B (0.50) | IL1BNLRP3TNFKCNH2 | |
| SCHEMBL26090664 | 0.86 | IL1B (0.49) | IL1BNLRP3TNFKCNH2 | |
| SCHEMBL26090675 | 0.86 | IL1B (0.49) | IL1BNLRP3TNFKCNH2 | |
| SCHEMBL31072365 | 0.84 | IL1B (0.47) | IL1BNLRP3TNFKCNH2 | |
| SCHEMBL26439655 | 0.84 | IL1B (0.47) | IL1BNLRP3TNFKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116102535-A | Nitrogen-containing compound, preparation method and application thereof | 索智生物科技（浙江）有限公司 | 2023-05-12 | — | — | CN | disclosed |
| WO-2023066377-A1 | NITROGEN-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 索智生物科技（浙江）有限公司 | 2023-04-27 | — | — | WO | disclosed |
| WO-2023066377-A1 | NITROGEN-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 索智生物科技（浙江）有限公司 | 2023-04-27 | — | — | WO | disclosed |