Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | PTPRB | P23467 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26091134 | 0.79 | CYP1A2 (0.46) | KMT2AMEN1ALDH1A1NPC1JAK2 | |
| SCHEMBL26091198 | 0.79 | PTPRB (0.49) | KMT2ALTB4R2NR3C1ALDH1A1NPC1 | |
| SCHEMBL7342383 | 0.74 | HDAC1 (0.69) | HDAC6HDAC1HDAC8KMT2ALTB4R2 | |
| SCHEMBL1334800 | 0.72 | HDAC1 (0.49) | HDAC6HDAC1HDAC8KMT2ALTB4R2 | |
| SCHEMBL5995235 | 0.71 | ALDH1A1 (0.54) | KMT2AMEN1ALDH1A1HTT | |
| SCHEMBL10312254 | 0.70 | CYP19A1 (0.57) | KMT2AMEN1NR3C1RAB9A | |
| SCHEMBL3058600 | 0.70 | RAB9A (0.51) | HDAC6HDAC1HDAC8KMT2ALTB4R2 | |
| SCHEMBL11117024 | 0.69 | DCUN1D1 (0.46) | HDAC6HDAC1HDAC8KMT2ALTB4R2 | |
| SCHEMBL11696683 | 0.69 | TSHR (0.64) | KMT2AMEN1NR3C1ALDH1A1KDM4E | |
| SCHEMBL19745672 | 0.68 | MEN1 (0.51) | HDAC6HDAC1HDAC8KMT2ALTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230129487-A1 | SMALL MOLECULE BCL-2 FUNCTIONAL CONVERTERS AS CANCER THERAPEUTICS | OREGON STATE UNIVERSITY (US) | 2023-04-27 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230129487-A1 | SMALL MOLECULE BCL-2 FUNCTIONAL CONVERTERS AS CANCER THERAPEUTICS | BCL2, BCL2L1, BCL2L13 | HDAC6 1843/4885HDAC1 1970/4885HDAC8 1907/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.