Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | TACR1 | P25103 | 2/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10500798 | 0.70 | LMNA (0.60) | DCUN1D1MEN1KMT2AALDH1A1 | |
| SCHEMBL1334800 | 0.70 | HDAC1 (0.49) | MEN1KMT2APTGDR2LTB4R2HDAC6 | |
| SCHEMBL11117279 | 0.69 | OPRM1 (0.40) | MEN1KMT2AOPRM1ALDH1A1 | |
| SCHEMBL7342383 | 0.69 | HDAC1 (0.69) | DCUN1D1MEN1KMT2APTGDR2KDM4E | |
| SCHEMBL26090579 | 0.69 | HDAC6 (0.51) | MEN1KMT2APTGDR2KDM4EALDH1A1 | |
| SCHEMBL11118511 | 0.69 | MMP9 (0.41) | MEN1KMT2AOPRM1 | |
| SCHEMBL2811090 | 0.69 | OPRM1 (0.56) | TACR1OPRM1OPRL1SLC6A2SLC6A4 | |
| SCHEMBL19745672 | 0.69 | MEN1 (0.51) | MEN1KMT2APTGDR2LTB4R2HDAC6 | |
| SCHEMBL4437768 | 0.68 | MEN1 (0.54) | MEN1KMT2ALTB4R2HDAC6HDAC1 | |
| SCHEMBL16221530 | 0.67 | HDAC6 (0.52) | LTB4R2HDAC6HDAC1HDAC8HDAC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0121972-A2 | N-aryl-alpha-amino-carboxamides | JANSSEN PHARMACEUTICA N.V. (BE) | 1984-10-17 | — | — | EP | disclosed |