Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 10/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SLC6A15 | Q9H2J7 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | UBE2N | P61088 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 2/20 | 0.33 |
| ▸ | PLG | P00747 | 2/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9383271 | 0.83 | ERN1 (0.49) | ERN1LMNAMAPK1RAB9ASLC6A15 | |
| SCHEMBL21611667 | 0.81 | DPP8 (0.37) | LMNARAB9ADPP8TMEM97SIGMAR1 | |
| SCHEMBL597800 | 0.79 | LMNA (0.45) | ERN1LMNAMAPK1RAB9ASLC6A15 | |
| SCHEMBL29306874 | 0.79 | ERN1 (0.42) | ERN1LMNAMAPK1RAB9ACYP3A4 | |
| SCHEMBL6686807 | 0.78 | ERN1 (0.51) | ERN1LMNAMAPK1RAB9ASLC6A15 | |
| SCHEMBL4195614 | 0.74 | LMNA (0.46) | ERN1LMNAMAPK1RAB9ASLC6A15 | |
| SCHEMBL8833559 | 0.73 | TSHR (0.48) | ERN1LMNAMAPK1RAB9A | |
| SCHEMBL3997516 | 0.73 | LMNA (0.45) | ERN1LMNAMAPK1RAB9ASLC6A15 | |
| SCHEMBL3992214 | 0.73 | LMNA (0.45) | ERN1LMNAMAPK1RAB9ASLC6A15 | |
| SCHEMBL10548331 | 0.72 | ERN1 (0.40) | ERN1LMNAMAPK1RAB9ASLC6A15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023069547-A1 | 5-MEMBERED HETEROARYL CARBOXAMIDE COMPOUNDS FOR TREATMENT OF HBV | ASSEMBLY BIOSCIENCES, INC. (US) | 2023-04-27 | — | — | WO | disclosed |
| WO-2023069547-A1 | 5-MEMBERED HETEROARYL CARBOXAMIDE COMPOUNDS FOR TREATMENT OF HBV | ASSEMBLY BIOSCIENCES, INC. (US) | 2023-04-27 | — | — | WO | disclosed |