Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 10/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SLC6A15 | Q9H2J7 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 2/20 | 0.35 |
| ▸ | PLG | P00747 | 2/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6686807 | 0.90 | ERN1 (0.51) | ERN1LMNAMAPK1RAB9ASLC6A15 | |
| SCHEMBL597800 | 0.90 | LMNA (0.45) | ERN1LMNAMAPK1RAB9ASLC6A15 | |
| SCHEMBL29306874 | 0.86 | ERN1 (0.42) | ERN1LMNAMAPK1RAB9AF10 | |
| SCHEMBL26091050 | 0.83 | ERN1 (0.44) | ERN1LMNAMAPK1RAB9ASLC6A15 | |
| SCHEMBL568818 | 0.79 | TSHR (0.47) | LMNAMAPK1RAB9ANPSR1 | |
| SCHEMBL8833559 | 0.76 | TSHR (0.48) | ERN1LMNAMAPK1RAB9AHSP90AA1 | |
| SCHEMBL17420837 | 0.75 | LMNA (0.42) | ERN1LMNAMAPK1RAB9ASLC6A15 | |
| SCHEMBL28479793 | 0.75 | CNR2 (0.44) | LMNASLC6A15HSP90AA1 | |
| SCHEMBL4195614 | 0.74 | LMNA (0.46) | ERN1LMNAMAPK1RAB9ASLC6A15 | |
| SCHEMBL9625561 | 0.74 | ERN1 (0.43) | ERN1LMNAMAPK1RAB9ASLC6A15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0394991-B1 | 1-Azabicyclo(3.2.0)Hept-2-Ene-2-carboxylic acid compounds | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-08-17 | — | — | EP | disclosed |
| US-5102877-A | Carbapenicillin antibiotics | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-04-07 | — | — | US | disclosed |
| EP-0394991-A1 | 1-Azabicyclo(3.2.0)Hept-2-Ene-2-carboxylic acid compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-10-31 | — | — | EP | disclosed |
| US-4299768-A | 1-Pyrrole- and 1-pyrrolidine-carboxylic acid derivatives and process for preparing the same | LABAZ (FR) | 1981-11-10 | — | — | US | disclosed |