SCHEMBL2609273

SCHEMBL2609273

O=c1cc2oc3ccccc3nc-2c2ccccc12

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.62
KMT2A Q03164 5/20 0.62
RAB9A P51151 5/20 0.62
NPC1 O15118 5/20 0.62
POLB P06746 3/20 0.62
PTPRA P18433 1/20 0.56
PTPRB P23467 1/20 0.56
MAPT P10636 3/20 0.54
ALDH1A1 P00352 3/20 0.54
KDM4E B2RXH2 3/20 0.54
RECQL P46063 2/20 0.54
ALPL P05186 1/20 0.54
ALPI P09923 1/20 0.54
ALPG P10696 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
MITF O75030 1/20 0.52
OPRD1 P41143 2/20 0.51
NR1I2 O75469 1/20 0.51
CHRM1 P11229 1/20 0.51
DRD2 P14416 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1108169 0.84 NPC1 (0.66) MEN1KMT2ARAB9ANPC1POLB
SCHEMBL3275224 0.84 KMT2A (0.62) MEN1KMT2ARAB9ANPC1POLB
SCHEMBL5561650 0.82 MEN1 (0.53) MEN1KMT2ARAB9ANPC1POLB
SCHEMBL1108126 0.81 RAB9A (0.62) MEN1KMT2ARAB9ANPC1POLB
SCHEMBL14347198 0.81 RAB9A (0.62) MEN1KMT2ARAB9ANPC1POLB
SCHEMBL8858355 0.81 NPC1 (0.76) MEN1KMT2ARAB9ANPC1POLB
SCHEMBL15385443 0.80 RAB9A (0.65) MEN1KMT2ARAB9ANPC1POLB
SCHEMBL31722939 0.80 NPC1 (0.74) MEN1KMT2ARAB9ANPC1POLB
SCHEMBL3274981 0.80 KMT2A (0.58) MEN1KMT2ARAB9ANPC1POLB
SCHEMBL14986327 0.80 NPC1 (0.74) MEN1KMT2ARAB9ANPC1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210147932-A1 FLUORESCENT PROBES FOR QUANTIFICATION OF DNA DAMAGE AND REPAIR THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2021-05-20 US claimed
EP-0747036-B1 A method of coloring hair with, and hair coloring compositions comprising, sulfo-containing water dispersible colored polymers CLAIROL INC (US) 2003-05-07 EP claimed
US-5831144-A Refrigeration compressor oil testing process and apparatus PASTORELLO JOHN (US) 1998-11-03 US claimed
EP-0400038-A1 WATER-DISSIPATABLE POLYESTER AND POLYESTER-AMIDES CONTAINING COPOLYMERIZED COLORANTS EASTMAN CHEMICAL COMPANY (US) 1990-12-05 EP claimed
WO-1989007118-A1 WATER-DISSIPATABLE POLYESTER AND POLYESTER-AMIDES CONTAINING COPOLYMERIZED COLORANTS EASTMAN KODAK COMPANY (US) 1989-08-10 WO claimed
US-4804719-A PRINTING INKS; COATINGS; HEAT AND COLD RESISTANCE EASTMAN KODAK COMPANY (US) 1989-02-14 US claimed
CN-112992967-B Photoelectric conversion element, image pickup element, stacked image pickup element, and solid-state image pickup device 索尼公司 2024-03-22 CN disclosed
US-11913884-B2 Visible light-activated dyes and methods of use thereof WILLIAM MARSH RICE UNIVERSITY (US) 2024-02-27 US disclosed
WO-2023205649-A1 CROSSLINKED ORGANOGELS FOR DRUG DELIVERY MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2023-10-26 WO disclosed
CN-116135846-A Preparation method and application of nile red and derivatives thereof 天津全和诚科技有限责任公司 2023-05-19 CN disclosed
EP-3327810-B1 IMAGING ELEMENT, MULTILAYER IMAGING ELEMENT AND SOLID-STATE IMAGING DEVICE SONY GROUP CORP (JP) 2022-11-02 EP disclosed
CN-107710413-B Photoelectric conversion element, imaging element, multilayer imaging element, and imaging device 索尼公司 2022-01-14 CN disclosed
CN-112992968-A Photoelectric conversion element, image pickup element, laminated image pickup element, and solid-state image pickup device 索尼公司 2021-06-18 CN disclosed
WO-1989007118-A1 WATER-DISSIPATABLE POLYESTER AND POLYESTER-AMIDES CONTAINING COPOLYMERIZED COLORANTS EASTMAN KODAK COMPANY (US) 1989-08-10 WO disclosed
US-4804719-A PRINTING INKS; COATINGS; HEAT AND COLD RESISTANCE EASTMAN KODAK COMPANY (US) 1989-02-14 US disclosed
US-4611056-A Benzo[A]phenothiazines and hydro-derivatives MERCK FROSST CANADA, INC. (CA) 1986-09-09 US disclosed
US-4604461-A 5-substituted-9-disubstituted amino-12-substituted carbonylbenzo[a]phenoxazines THE HILTON-DAVIS CHEMICAL CO. (US) 1986-08-05 US disclosed
EP-0170967-A1 Substituted benzophenoxazines, method for preparing same and use thereof in electrochromic recording systems THE HILTON - DAVIS CHEMICAL COMPANY (US) 1986-02-12 EP disclosed
US-4570171-A Electrochromic marking systems THE HILTON-DAVIS CHEMICAL CO. (US) 1986-02-11 US disclosed
EP-0136893-A2 Benzo[a]phenothiazines and hydro-derivatives and pharmaceutical compositions containing them MERCK FROSST CANADA INC. (CA) 1985-04-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11913884-B2 Visible light-activated dyes and methods of use thereof HCCS, CLTB, ALDH1A2 MEN1 3117/4885KMT2A 3471/4885RAB9A 509/4885
US-20210147932-A1 FLUORESCENT PROBES FOR QUANTIFICATION OF DNA DAMAGE AND REPAIR UNG, OGG1, FEN1 MEN1 4141/4885KMT2A 3582/4885RAB9A 3002/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.