SCHEMBL2609280

SCHEMBL2609280

OCCCCCCCCCCC[n+]1ccc(-c2cc[n+](CCCCCCCCCCCO)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.61
TP53 P04637 1/20 0.61
CYP1A2 P05177 1/20 0.61
CYP2D6 P10635 1/20 0.61
MAPT P10636 1/20 0.61
CYP2C9 P11712 1/20 0.61
CYP2C19 P33261 1/20 0.61
KMT2A Q03164 1/20 0.61
HTT P42858 2/20 0.59
KDM4E B2RXH2 1/20 0.59
NPC1 O15118 1/20 0.59
LMNA P02545 1/20 0.59
RAB9A P51151 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
BCHE P06276 10/20 0.44
ACHE P22303 10/20 0.44
CHKA P35790 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2609284 1.00 MEN1 (0.61) MEN1TP53CYP1A2CYP2D6MAPT
Bromide SCHEMBL7170664 0.98 MEN1 (0.59) MEN1TP53CYP1A2CYP2D6MAPT
SCHEMBL5711022 0.92 MEN1 (0.53) MEN1TP53CYP1A2CYP2D6MAPT
SCHEMBL2609281 0.90 MEN1 (0.62) MEN1TP53CYP1A2CYP2D6MAPT
SCHEMBL5711020 0.88 MEN1 (0.50) MEN1TP53CYP1A2CYP2D6MAPT
SCHEMBL5710989 0.88 MAPT (0.50) MEN1TP53CYP1A2CYP2D6MAPT
SCHEMBL5710972 0.84 ALDH1A1 (0.54) MEN1TP53CYP1A2CYP2D6MAPT
SCHEMBL7170348 0.84 MEN1 (0.46) MEN1TP53CYP1A2CYP2D6MAPT
Bromide SCHEMBL7169216 0.82 ALDH1A1 (0.53) MEN1TP53CYP1A2CYP2D6MAPT
SCHEMBL21490437 0.80 CHRNA7 (0.46) MEN1TP53CYP1A2CYP2D6MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10464900-B2 Electrochromic compounds with improved color stability in their radical states GENTEX CORPORATION (US) 2019-11-05 US disclosed
US-20180346421-A1 ELECTROCHROMIC COMPOUNDS WITH IMPROVED COLOR STABILITY IN THEIR RADICAL STATES GENTEX CORPORATION 2018-12-06 US disclosed
US-10040763-B2 Electrochromic compounds with improved color stability in their radical states GENTEX CORPORATION (US) 2018-08-07 US disclosed
US-10040763-B2 Electrochromic compounds with improved color stability in their radical states GENTEX CORPORATION (US) 2018-08-07 US disclosed
US-20160229803-A1 ELECTROCHROMIC COMPOUNDS WITH IMPROVED COLOR STABILITY IN THEIR RADICAL STATES GENTEX CORPORATION 2016-08-11 US disclosed
US-20160229803-A1 ELECTROCHROMIC COMPOUNDS WITH IMPROVED COLOR STABILITY IN THEIR RADICAL STATES GENTEX CORPORATION 2016-08-11 US disclosed
US-8294975-B2 Automotive rearview mirror assembly DONNELLY CORPORATION (US) 2012-10-23 US disclosed
US-8164817-B2 Method of forming a mirrored bent cut glass shape for vehicular exterior rearview mirror assembly DONNELLY CORPORATION (US) 2012-04-24 US disclosed
US-20110045172-A1 METHOD OF FORMING A MIRRORED BENT CUT GLASS SHAPE FOR VEHICULAR EXTERIOR REARVIEW MIRROR ASSEMBLY DONNELLY CORPORATION (US) 2011-02-24 US disclosed
US-7202987-B2 Electrochromic polymeric solid films, manufacturing electrochromic devices using such solid films, and processes for making such solid films and devices DONNELLY CORPORATION (US) 2007-04-10 US disclosed
EP-1027397-B1 ELECTROCHROME POLYMER SYSTEMS BAYER INNOVATION GMBH (DE) 2006-10-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10464900-B2 Electrochromic compounds with improved color stability in their radical states ETV6, PMS2, EED MEN1 2956/4885TP53 308/4885CYP1A2 650/4885
US-10040763-B2 Electrochromic compounds with improved color stability in their radical states ETV6, CYCS, SCO2 MEN1 3053/4885TP53 676/4885CYP1A2 515/4885
US-20160229803-A1 ELECTROCHROMIC COMPOUNDS WITH IMPROVED COLOR STABILITY IN THEIR RADICAL STATES ETV6, CYCS, SCO2 MEN1 3053/4885TP53 676/4885CYP1A2 515/4885
US-20180346421-A1 ELECTROCHROMIC COMPOUNDS WITH IMPROVED COLOR STABILITY IN THEIR RADICAL STATES ETV6, PMS2, EED MEN1 2956/4885TP53 308/4885CYP1A2 650/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.