SCHEMBL26096078

SCHEMBL26096078

Cc1cc(F)c(F)c(OCc2ccccc2)c1

nearest known ligand 0.51

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.51
MAPK1 P28482 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
MRGPRX4 Q96LA9 3/20 0.48
KDM1A O60341 7/20 0.48
STAT3 P40763 1/20 0.45
HTT P42858 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
LIPE Q05469 1/20 0.44
HTR1A P08908 1/20 0.43
SLC6A2 P23975 1/20 0.43
SLC6A4 P31645 1/20 0.43
SLC6A3 Q01959 1/20 0.43
DHODH Q02127 1/20 0.42
FFAR1 O14842 1/20 0.42
NPC1 O15118 1/20 0.42
PTGER1 P34995 1/20 0.42
FFAR4 Q5NUL3 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28643177 0.84 MRGPRX4 (0.49) MAPTMAPK1TDP1L3MBTL1MRGPRX4
SCHEMBL24750717 0.84 MAPT (0.49) MAPTMAPK1TDP1L3MBTL1MRGPRX4
SCHEMBL12799725 0.83 BCHE (0.45) MAPTMAPK1TDP1L3MBTL1MRGPRX4
SCHEMBL17367259 0.81 MAPT (0.53) MAPTMAPK1TDP1L3MBTL1MRGPRX4
SCHEMBL171841 0.81 MRGPRX4 (0.68) MAPTMAPK1TDP1L3MBTL1MRGPRX4
SCHEMBL15057786 0.81 KDM1A (0.47) MAPTMAPK1TDP1L3MBTL1MRGPRX4
SCHEMBL12799710 0.81 KDM1A (0.49) MAPTMAPK1TDP1L3MBTL1MRGPRX4
SCHEMBL24861784 0.81 MAOB (0.53) MAPTMAPK1TDP1L3MBTL1MRGPRX4
SCHEMBL18495767 0.80 LIPE (0.53) MAPTMAPK1TDP1L3MBTL1MRGPRX4
SCHEMBL3795791 0.80 KDM1A (0.64) MAPTMAPK1TDP1L3MBTL1MRGPRX4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4423098-A1 ELECTRONIC SWITCHING DEVICE Merck Patent GmbH (DE) 2024-09-04 EP disclosed
CN-118159545-A Electronic switching device 默克专利有限公司 2024-06-07 CN disclosed
WO-2023072795-A1 ELECTRONIC SWITCHING DEVICE MERCK PATENT GMBH (DE) 2023-05-04 WO disclosed
WO-2023072795-A1 ELECTRONIC SWITCHING DEVICE MERCK PATENT GMBH (DE) 2023-05-04 WO disclosed
EP-4174077-A1 ELECTRONIC SWITCHING DEVICE Merck Patent GmbH (DE) 2023-05-03 EP disclosed
EP-4174077-A1 ELECTRONIC SWITCHING DEVICE Merck Patent GmbH (DE) 2023-05-03 EP disclosed