Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.48 |
| ▸ | STAT3 | P40763 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM1A | O60341 | 7/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | LIPE | Q05469 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7436805 | 0.89 | MAPT (0.56) | MRGPRX4MAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL4540283 | 0.84 | KDM1A (0.56) | MRGPRX4MAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL26096078 | 0.84 | MAPT (0.51) | MRGPRX4MAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL31088870 | 0.84 | MAPT (0.51) | MRGPRX4MAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL31166737 | 0.83 | MAOB (0.50) | MAPTMAPK1TDP1L3MBTL1SMN1; SMN2 | |
| SCHEMBL171841 | 0.82 | MRGPRX4 (0.68) | MRGPRX4MAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL17367259 | 0.82 | MAPT (0.53) | MRGPRX4MAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL24750717 | 0.81 | MAPT (0.49) | MRGPRX4MAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL25085876 | 0.81 | HTR1A (0.43) | MRGPRX4MAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL15180164 | 0.79 | MAPT (0.53) | MRGPRX4MAPTMAPK1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113573713-A | Ion channel modulators | 普拉克西斯精密药物股份有限公司 | 2021-10-29 | — | — | CN | disclosed |