Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 10/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2609511 | 1.00 | VDR (0.73) | VDR | |
| SCHEMBL15371108 | 1.00 | VDR (0.73) | VDR | |
| SCHEMBL859703 | 1.00 | VDR (0.73) | VDR | |
| SCHEMBL14647794 | 1.00 | VDR (0.73) | VDR | |
| SCHEMBL9009975 | 1.00 | VDR (0.73) | VDR | |
| SCHEMBL15371112 | 1.00 | VDR (0.73) | VDR | |
| SCHEMBL13759538 | 1.00 | VDR (0.73) | VDR | |
| SCHEMBL14494338 | 1.00 | VDR (0.73) | VDR | |
| SCHEMBL14494340 | 0.94 | VDR (0.73) | VDR | |
| SCHEMBL13899800 | 0.94 | VDR (0.73) | VDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170326159-A1 | METHODS OF USE TO ORALLY AND TOPICALLY TREAT ACNE AND OTHER SKIN CONDITIONS BY ADMINISTERING A 19-NOR CONTAINING VITAMIN D ANALOG WITH OR WITHOUT A RETINOID | WISCONSIN ALUMNI RES FOUND (US) | 2017-11-16 | — | — | US | disclosed |
| US-20170326159-A1 | METHODS OF USE TO ORALLY AND TOPICALLY TREAT ACNE AND OTHER SKIN CONDITIONS BY ADMINISTERING A 19-NOR CONTAINING VITAMIN D ANALOG WITH OR WITHOUT A RETINOID | WISCONSIN ALUMNI RES FOUND (US) | 2017-11-16 | — | — | US | disclosed |
| EP-1848442-B1 | 2-METHYLENE-19-NOR-(20S-24EPI)-1ALPHA,25-DIHYDROXYVITAMINE-D2 | WISCONSIN ALUMNI RES FOUND (US) | 2012-04-25 | — | — | EP | disclosed |
| US-7511030-B2 | 2-methylene-19-nor-(20S-24epi)-1α,25-dihydroxyvitamin D2 | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2009-03-31 | — | — | US | disclosed |
| US-7511030-B2 | 2-methylene-19-nor-(20S-24epi)-1α,25-dihydroxyvitamin D2 | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2009-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170326159-A1 | METHODS OF USE TO ORALLY AND TOPICALLY TREAT ACNE AND OTHER SKIN CONDITIONS BY ADMINISTERING A 19-NOR CONTAINING VITAMIN D ANALOG WITH OR WITHOUT A RETINOID | CYP24A1, CYP2R1, VDR | VDR 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.