SCHEMBL9009975

SCHEMBL9009975

C=C1[C@H](O)CC(=C/C=C2\CCC[C@]3(C)[C@@H]([C@H](C)/C=C/[C@@H](C)C(C)(C)O)CC[C@@H]23)C[C@H]1O

nearest known ligand 0.73

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ VDR P11473 10/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2609511 1.00 VDR (0.73) VDR
SCHEMBL2609785 1.00 VDR (0.73) VDR
SCHEMBL15371108 1.00 VDR (0.73) VDR
SCHEMBL859703 1.00 VDR (0.73) VDR
SCHEMBL14647794 1.00 VDR (0.73) VDR
SCHEMBL15371112 1.00 VDR (0.73) VDR
SCHEMBL13759538 1.00 VDR (0.73) VDR
SCHEMBL14494338 1.00 VDR (0.73) VDR
SCHEMBL14494340 0.94 VDR (0.73) VDR
SCHEMBL13899800 0.94 VDR (0.73) VDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8188064-B2 Reducing cell differentiation of adipocyte; reducing body fat WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2012-05-29 — — US disclosed
US-8188064-B2 Reducing cell differentiation of adipocyte; reducing body fat WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2012-05-29 — — US disclosed
US-7745404-B2 Use of calcitonin and calcitonin-like peptides to treat and prevent multiple sclerosis WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2010-06-29 — — US disclosed
US-7745404-B2 Use of calcitonin and calcitonin-like peptides to treat and prevent multiple sclerosis WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2010-06-29 — — US disclosed
US-7566696-B2 Use of calcitonin and calcitonin-like peptides to treat and prevent multiple sclerosis WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2009-07-28 — — US disclosed
US-7566696-B2 Use of calcitonin and calcitonin-like peptides to treat and prevent multiple sclerosis WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2009-07-28 — — US disclosed
US-20080146491-A1 USE OF CALCITONIN AND CALCITONIN-LIKE PEPTIDES TO TREAT AND PREVENT MULTIPLE SCLEROSIS DELUCA HECTOR F 2008-06-19 — — US disclosed
US-20080146491-A1 USE OF CALCITONIN AND CALCITONIN-LIKE PEPTIDES TO TREAT AND PREVENT MULTIPLE SCLEROSIS DELUCA HECTOR F 2008-06-19 — — US disclosed
US-20070105774-A1 Administering an appropriate dosage schedule of a bone calcium resorption inhibitor like alendronate and a toxic dose of a vitamin D compounds like 1, alpha 25-dihydroxyvitamin D3 without developing hypercalcemia WISCONSIN ALUMNI RESEARCH FOUNDATION 2007-05-10 — — US disclosed
US-20070105774-A1 Administering an appropriate dosage schedule of a bone calcium resorption inhibitor like alendronate and a toxic dose of a vitamin D compounds like 1, alpha 25-dihydroxyvitamin D3 without developing hypercalcemia WISCONSIN ALUMNI RESEARCH FOUNDATION 2007-05-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070105774-A1 Administering an appropriate dosage schedule of a bone calcium resorption inhibitor like alendronate and a toxic dose of a vitamin D compounds like 1, alpha 25-dihydroxyvitamin D3 without developing hypercalcemia CALCA, CALCRL, CYP24A1 VDR 7/4885
US-20080146491-A1 USE OF CALCITONIN AND CALCITONIN-LIKE PEPTIDES TO TREAT AND PREVENT MULTIPLE SCLEROSIS CALCA, CALCB, CALCRL VDR 5/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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