Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | ALPG | P10696 | 1/20 | 0.34 |
| ▸ | GCGR | P47871 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | FBP1 | P09467 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10816690 | 0.74 | LMNA (0.51) | ALDH1A1MAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL15209996 | 0.72 | CYP1A2 (0.41) | ALDH1A1MAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL23706910 | 0.69 | ALDH1A1 (0.40) | ALDH1A1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL26133650 | 0.69 | SMN1; SMN2 (0.33) | ALDH1A1MAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL8156547 | 0.66 | CYP1A2 (0.36) | ALDH1A1MAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL774785 | 0.66 | CYP1A2 (0.73) | ALDH1A1MAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL9622398 | 0.66 | SMN1; SMN2 (0.71) | ALDH1A1MAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL13766355 | 0.65 | SMN1; SMN2 (0.47) | ALDH1A1MAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL3802060 | 0.65 | FBP1 (0.46) | ALDH1A1MAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL27834024 | 0.65 | PPARA (0.55) | ALDH1A1CYP1A2CYP2D6FBP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230138851-A1 | NOVEL ALKYNE DERIVATIVES | CARNA BIOSCIENCES, INC. (JP) | 2023-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230138851-A1 | NOVEL ALKYNE DERIVATIVES | DYRK1B, DYRK3, DYRK2 | PTGS1 3003/4885PTGS2 2849/4885ALDH1A1 1453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.