Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 3/20 | 0.64 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.64 |
| ▸ | TUBB | P07437 | 2/20 | 0.58 |
| ▸ | CDK1 | P06493 | 1/20 | 0.55 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.51 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.51 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.51 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.51 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.51 |
| ▸ | POLA1 | P09884 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 2/20 | 0.50 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23675369 | 0.87 | TMPRSS4 (0.67) | P2RX1TMPRSS4TUBBCDK1P2RX4 | |
| SCHEMBL30100436 | 0.87 | TMPRSS4 (0.67) | P2RX1TMPRSS4TUBBCDK1P2RX4 | |
| SCHEMBL13812639 | 0.87 | P2RX1 (0.66) | P2RX1TMPRSS4TUBBCDK1P2RX4 | |
| SCHEMBL23675446 | 0.87 | TUBB (0.72) | P2RX1TMPRSS4TUBBCDK1P2RX4 | |
| SCHEMBL13812912 | 0.86 | TMPRSS4 (0.68) | P2RX1TMPRSS4TUBBCDK1P2RX4 | |
| SCHEMBL13812915 | 0.84 | P2RX1 (0.70) | P2RX1TMPRSS4TUBBCDK1P2RX4 | |
| SCHEMBL23675443 | 0.83 | P2RX1 (0.64) | P2RX1TMPRSS4TUBBCDK1P2RX4 | |
| SCHEMBL26097052 | 0.82 | HPGD (0.63) | P2RX1TMPRSS4TUBBCDK1POLA1 | |
| SCHEMBL13236587 | 0.81 | TUBB (0.75) | P2RX1TMPRSS4TUBBCDK1POLA1 | |
| SCHEMBL30100461 | 0.81 | TUBB (0.75) | P2RX1TMPRSS4TUBBCDK1POLA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230140290-A1 | SALICYLAMIDE DERIVATIVES AND RELATED METHODS OF MAKING | THE BOARD OF REGENTS OF THE UNIV OF TEXAS SY (US) | 2023-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230140290-A1 | SALICYLAMIDE DERIVATIVES AND RELATED METHODS OF MAKING | EIF2AK2, SARS1, ACE | P2RX1 3088/4885TMPRSS4 526/4885TUBB 3158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.