Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 15/20 | 0.57 |
| ▸ | KDR | P35968 | 5/20 | 0.52 |
| ▸ | KIT | P10721 | 4/20 | 0.51 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.50 |
| ▸ | FLT1 | P17948 | 3/20 | 0.50 |
| ▸ | FLT4 | P35916 | 3/20 | 0.50 |
| ▸ | RET | P07949 | 2/20 | 0.50 |
| ▸ | KIF5B | P33176 | 2/20 | 0.50 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.50 |
| ▸ | TEK | Q02763 | 2/20 | 0.50 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.50 |
| ▸ | PLK4 | O00444 | 1/20 | 0.50 |
| ▸ | CIT | O14578 | 1/20 | 0.50 |
| ▸ | GAK | O14976 | 1/20 | 0.50 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.50 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.50 |
| ▸ | STK10 | O94804 | 1/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.50 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30393893 | 0.91 | EGFR (0.64) | EGFRKDRKITFGFR1FLT1 | |
| SCHEMBL26100098 | 0.84 | EGFR (0.56) | EGFRKDRKITFGFR1FLT1 | |
| SCHEMBL26101933 | 0.83 | EGFR (0.49) | EGFRKDRKITFGFR1FLT1 | |
| SCHEMBL30394062 | 0.83 | EGFR (0.49) | EGFRKDRKITFGFR1FLT1 | |
| SCHEMBL26100102 | 0.82 | EGFR (0.62) | EGFRKDRKIT | |
| SCHEMBL26102560 | 0.80 | EGFR (0.48) | EGFRKDRKITFGFR1FLT1 | |
| SCHEMBL26100068 | 0.80 | EGFR (0.57) | EGFRKDRKITFGFR1FLT1 | |
| SCHEMBL30394491 | 0.80 | EGFR (0.57) | EGFRKDRKITFGFR1FLT1 | |
| SCHEMBL30394389 | 0.79 | KDR (0.53) | EGFRKDRKIT | |
| SCHEMBL29238264 | 0.79 | KDR (0.53) | EGFRKDRKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023075529-A1 | QUINAZOLINE DERIVATIVE COMPOUND AND USE THEREOF | 보로노이바이오 주식회사 | 2023-05-04 | — | — | WO | disclosed |