Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 5/20 | 0.47 |
| ▸ | KIT | P10721 | 5/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.44 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26102887 | 0.85 | EGFR (0.53) | EGFRKITIRAK4KDRPDGFRB | |
| SCHEMBL26100134 | 0.84 | KIT (0.46) | EGFRKITPDE10AKDM1AKDR | |
| SCHEMBL26098271 | 0.83 | EGFR (0.46) | EGFRKITIRAK1IRAK4PDK1 | |
| SCHEMBL26099903 | 0.82 | EGFR (0.45) | EGFRKITPDE10AIRAK1IRAK4 | |
| SCHEMBL26100658 | 0.81 | EGFR (0.45) | EGFRKITIRAK1IRAK4PDK1 | |
| SCHEMBL4725258 | 0.80 | KDM1A (0.57) | EGFRKITIRAK1IRAK4KDM1A | |
| SCHEMBL26100111 | 0.79 | EGFR (0.47) | EGFRKITIRAK1IRAK4PDK1 | |
| SCHEMBL26098937 | 0.79 | KIT (0.56) | EGFRKITIRAK1IRAK4KDM1A | |
| SCHEMBL30394612 | 0.78 | EGFR (0.54) | EGFRIRAK4KDRPDGFRB | |
| SCHEMBL26099908 | 0.78 | EGFR (0.54) | EGFRKITIRAK4KDRPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023075529-A1 | QUINAZOLINE DERIVATIVE COMPOUND AND USE THEREOF | 보로노이바이오 주식회사 | 2023-05-04 | — | — | WO | claimed |