Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 8/20 | 0.46 |
| ▸ | KDR | P35968 | 3/20 | 0.43 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.42 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.42 |
| ▸ | KIT | P10721 | 2/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.40 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.40 |
| ▸ | BRAF | P15056 | 2/20 | 0.40 |
| ▸ | RAF1 | P04049 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26102475 | 0.87 | KDR (0.44) | EGFRKDRKITPDK1ERBB2 | |
| SCHEMBL26100658 | 0.85 | EGFR (0.45) | EGFRKDRIRAK1IRAK4KIT | |
| SCHEMBL26099906 | 0.83 | EGFR (0.47) | EGFRKDRIRAK1IRAK4KIT | |
| SCHEMBL26100111 | 0.83 | EGFR (0.47) | EGFRKDRIRAK1IRAK4KIT | |
| SCHEMBL26100106 | 0.83 | RXRA (0.46) | EGFRKDRIRAK1IRAK4KIT | |
| SCHEMBL26102818 | 0.82 | EGFR (0.54) | EGFRKDRIRAK4KITAURKB | |
| SCHEMBL26098276 | 0.82 | EGFR (0.54) | EGFRKDRIRAK4AURKBBRAF | |
| SCHEMBL30394612 | 0.82 | EGFR (0.54) | EGFRKDRIRAK4AURKBBRAF | |
| SCHEMBL26098937 | 0.78 | KIT (0.56) | EGFRKDRIRAK1IRAK4KIT | |
| SCHEMBL4725258 | 0.77 | KDM1A (0.57) | EGFRKDRIRAK1IRAK4KIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023075529-A1 | QUINAZOLINE DERIVATIVE COMPOUND AND USE THEREOF | 보로노이바이오 주식회사 | 2023-05-04 | — | — | WO | claimed |